diplomsko delo
Katarina Barbara Reberc (Author), Krištof Kranjc (Mentor)

Abstract

V diplomskem delu so predstavljeni 2H-piran-2-oni; opisana je njihova prisotnost v naravi in različne lastnosti ter možnosti terapevtske uporabe naravno prisotnih produktov, ki vsebujejo piranonski skelet. V literaturi sem poiskala različne metode sinteze, med katerimi so vključeni tudi novejši, bolj »zeleni« pristopi, na primer z mikrovalovi, z uporabo CO2 kot C1 sintona ali z biotehnološkim pridobivanjem. 2H-piran-2-oni sodelujejo v mnogih različnih reakcijah, preko katerih pridemo do zelo raznolikih produktov, na primer različni kisikovih ali dušikovih heterociklov in molekul, ki so uporabne za nadaljnjo sintezo naravno prisotnih spojin. Nekaj več pozornosti je namenjene Diels‒Alderjevim cikloadicijam, v katerih 2H-piran-2-oni predstavljajo zelo dobre diene. Vključena je tudi spektroskopska analiza 2H-piran-2-onov, ki predstavlja pomemben del organske sinteze. Na koncu sta opisani še dve sintezi 2H-piran-2-onov, ki sem jih izvedla v laboratoriju.

Keywords

organske spojine;heterociklične spojine;organska sinteza;derivati piranov;piranoni;2H-piran-2-oni;Diels-Alderjeva reakcija;spektroskopska analiza;diplomska dela;

Data

Language: Slovenian
Year of publishing:
Typology: 2.11 - Undergraduate Thesis
Organization: UL FKKT - Faculty of Chemistry and Chemical Technology
Publisher: [K. B. Reberc]
UDC: 547.81.057(043.2)
COBISS: 26754563 Link will open in a new window
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Downloads: 169
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Other data

Secondary language: English
Secondary title: An overview of 2H-pyran-2-ones and synthesis of two substituted 3-benzoylamino-2H-pyran-2-ones
Secondary abstract: 2H-Pyran-2-ones are presented in this thesis; their presence, different characteristics and possible therapeutic uses of natural compounds, which possess the pyranone motif, are described. I investigated different methods of synthesis described in the literature, which include more recent and “greener” approaches, for example microwave-assisted synthesis, incorporation of CO2 as a C1 synthon or biotechnology-derived products. A little more attention is devoted to Diels‒Alder cycloadditions, in which 2H-pyran-2-ones participate as very favorable dienes. Spectroscopic analysis is also included, as it is a very important part of organic synthesis. At the end, two syntheses of 2H-pyran-2-ones which I have carried out in the laboratory, are described.
Secondary keywords: 2H-pyran-2-ones;organic synthesis;heterocyclic compounds;spectroscopic analysis;
Type (COBISS): Bachelor thesis/paper
Study programme: 1000373
Thesis comment: Univ. v Ljubljani, Fak. za kemijo in kemijsko tehnologijo, UNI Kemija
Pages: 37 str.
ID: 12003881