Let the biocatalyst flow

Abstract

Industrial biocatalysis has been identified as one of the key enabling technologies that, together with the transition to continuous processing, offers prospects for the development of cost-efficient manufacturing with high-quality products and low waste generation. This feature article highlights the role of miniaturized flow reactors with free enzymes and cells in the success of this endeavor with recent examples of their use in single or multiphase reactions. Microfluidics-based droplets enable ultrahigh-throughput screening and rapid biocatalytic process development. The use of unique microreactor configurations ensures highly efficient contacting of multiphase systems, resulting in process intensification and avoiding problems encountered in conventional batch processing. Further integration of downstream units offers the possibility of biocatalyst recycling, contributing to the cost-efficiency of the process. The use of environmentally friendly solvents supports effective reaction engineering, and thus paves the way for these highly selective catalysts to drive sustainable production.

Keywords

biocatalysis;microflow reactor;ionic liquids;aqueous two-phase systems;

Data

Language:	English
Year of publishing:	2021
Typology:	1.02 - Review Article
Organization:	UL FKKT - Faculty of Chemistry and Chemical Technology
UDC:	66.098
COBISS:	47790851
ISSN:	1580-3155
Views:	306
Downloads:	99
Average score:	0 (0 votes)
Metadata:

Other data

Secondary language:	Slovenian
Secondary keywords:	biokataliza;mikropretočni reaktorji;ionske kapljevine;dvofazni vodni sistem;
Type (COBISS):	Article
Pages:	str. 1-16
Volume:	ǂVol. ǂ68
Issue:	ǂno. ǂ1
Chronology:	2021
DOI:	10.17344/acsi.2020.6488
ID:	12907170