ǂa ǂsystematic review with meta-analysis
Jasna But Hadžić (Author), Mirza Dervišević (Author), Damir Karpljuk (Author), Mateja Videmšek (Author), Edvin Dervišević (Author), Armin Paravlić (Author), Vedran Hadžić (Author), Katja Tomažin (Author)

Abstract

The six-minute walk test (6MWT) is a widely used test for the indirect measurement of cardiorespiratory fitness in various cancer populations. Although the 6MWT is a simple test, there are no normative values for breast cancer survivors (BCS) or comparisons of results with healthy counterparts. A systematic review with a meta-analysis was carried out, which included studies from 2007 to 2020. Ninety-one studies were found, 21 of which were included in the quantitative synthesis. Among them were 9 randomized controlled trials (RCT), 8 prospective cohort studies and 4 cross-sectional studies. A total of 1084 BCS were included. Our results revealed that healthy subjects (n = 878) covered a significantly greater distance than BCS during the 6MWT (589.9 m vs. 477.4 m, p < 0.001), and the results of the meta-regression analysis showed that the 6MWD was predicted by the participants’ BMI (p < 0.001), but not by their age (p = 0.070). After adjustment for BMI, the healthy subjects also covered greater distances than the BCS (103 m; p < 0.001). The normative values of 6MWT were presented for BCS. Besides, 6MWT distances distinguish between their healthy counterparts, therefore, the 6MWT distance is a relevant parameter for the assessment and monitoring of cardiorespiratory fitness in medical and exercise interventions for BCS.

Keywords

sport;female;cardio-respiratory fitness;reference values;breast cancer;six minute walk test;

Data

Language: English
Year of publishing:
Typology: 1.02 - Review Article
Organization: UL FŠ - Faculty of Sport
UDC: 616-006:796.01
COBISS: 54053379 Link will open in a new window
ISSN: 1660-4601
Views: 161
Downloads: 63
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Other data

Secondary language: Slovenian
Secondary keywords: šport;ženske;kardio respiratorni fitnes;srčno žilni fitnes;normativne vrednosti;test šest minutne hoje;rak dojk;
Type (COBISS): Article
Pages: str. 1-13
Volume: ǂVol. ǂ18
Issue: ǂiss. ǂ5, ǂart. ǂ2591
Chronology: 2021
DOI: 10.3390/ijerph18052591
ID: 14562742