Vpliv vremena na počutje bolnikov z multiplo sklerozo

magistrsko delo

Anita Pirečnik Noč (Author), Majda Pajnkihar (Mentor), Saša Šega (Co-mentor)

Abstract

Čeprav je o vplivu vremena na človekovo zdravje med prvimi pisal že grški zdravnik Hipokrat in v zadnjem času vse več strokovnjakov proučuje vpliv vremena na počutje ljudi, je še veliko neznanega glede vpliva vremena na bolnike z multiplo sklerozo. Namen raziskave je ugotoviti, ali vremenske razmere (temperatura in vlažnost zraka, zračni pritisk, prisotnost padavin) vplivajo na subjektivno počutje bolnikov ter ali je vpliv klimatskih spremenljivk na subjektivno počutje odvisen od stopnje prizadetosti in od imunomodulatornega zdravljenja. Metodologija raziskovanja. Izvedli smo prospektivno deskriptivno raziskavo pri bolnikih z multiplo sklerozo, ki prihajajo na redne kontrole v Center za multiplo sklerozo. V raziskavo smo uvrstili 310 bolnikov z multiplo sklerozo, vsakega od njih smo natančno seznanili z raziskavo in pravico, da sodelovanje brez posledic zavrne. Vpliv vremenskih dejavnikov na subjektivno počutje bolnikov smo analizirali z metodo multiple regresije. Rezultati. Raziskava je statistično potrdila pomemben vpliv vremenskih dejavnikov na subjektivno počutje bolnikov z multiplo sklerozo. Neodvisna napovedna dejavnika slabšega subjektivnega počutja sta bila povečana vlaga (regresijski koeficient – 0.14; 95% CI – 0.26 – 0.02; p=0.024) in hitre spremembe zračnega tlaka (regresijski koeficient – 8.72; 95% CI – 18.04 -0.60; p=0.067). Pomemben izsledek raziskave je tudi dejstvo, da je vpliv vremenskih dejavnikov na subjektivno počutje lahko odvisen od stopnje nevrološke prizadetosti in imunomodulatornega zdravljenja. Sklep. Izsledki raziskave bodo v prihodnje pripomogli k boljšemu razumevanju slabšega počutja bolnikov z multiplo sklerozo ob določenih vremenskih pogojih, prav tako pa bodo bolniki ob spremljanju vremenskih napovedi lahko pripravljeni na slabše počutje ob povečani vlagi ali spremembi zračnega tlaka.

Keywords

multipla skleroza;vreme;subjektivno počutje;

Data

Language:	Slovenian
Year of publishing:	2012
Source:	Maribor
Typology:	2.09 - Master's Thesis
Organization:	UM FZV - Faculty of Health Sciences
Publisher:	[A. Pirečnik Noč]
UDC:	616.832-004
COBISS:	1828772
Views:	3787
Downloads:	370
Average score:	0 (0 votes)
Metadata:

Other data

Secondary language:	English
Secondary title:	INFLUENCE OF WEATHER CONDITION ON PATIENTS WITH MULTIPLE SCLEROSIS
Secondary abstract:	Despite the fact that first reports on impact of climate factors on human well-being have been made by the father of medicine, Hippocrates, and that area continues to be interesting also nowadays, little is known about the influences of weather on multiple sclerosis. In the present study we therefore investigated possible impact of climate factors (air temperature, humidity, barometric pressure, precipitation) on well–being of patients with multiple sclerosis and if such influence is dependent upon neurological impairment and presence of immunomodulatory treatment. Research methodology. We conducted prospective descriptive cohort study in patients with multiple sclerosis followed at the Center for multiple sclerosis in Ljubljana. A total of 310 patients, who gave written informed consent, were included. Multiple regression was used to identify climate factors independently influencing well-being of the patients. Results. Study revealed statistically significant influence of climate factors on subjective well-being of patients. Multiple regression revealed that increased humidity (regression coefficient - 0.14; 95% CI - 0.26 - 0.02; p=0.024) and rapid changes in barometric pressure (regression coefficient – 8.72; 95% CI - 18.04 - 0.60; p=0.067) were independent negative predictors of well-being. Post-hoc subgroup analysis revealed that influence of weather may be different according to the neurological impairment and presence of immunomodulatory therapy. Conclusion. Our study will help us to better understand worse subjective well-being of patients with multiple sclerosis during particular weather conditions. On the other hand, these findings may be useful also for patients to be aware that increased humidity and rapid changes in barometric pressure may worsen their subjective well-being.
Secondary keywords:	multiple sclerosis;weather;subjective well-being;
URN:	URN:SI:UM:
Type (COBISS):	Master's thesis/paper
Thesis comment:	Univ. v Mariboru, Fak. za zdravstvene vede
Pages:	VI, 51 f., 8 f. pril.
Keywords (UDC):	applied sciences;medicine;technology;uporabne znanosti;medicina;tehnika;medical sciences;medicina;pathology;clinical medicine;patologija;klinična medicina;neurology;neuropathology;nervous system;nevrologija;nevropatologija;živčevje;
ID:	15729