diplomsko delo
Šemsa Zec (Author), Matevž Pompe (Mentor)

Abstract

Vitamin C je danes že vsem dobro poznan zaradi številnih pozitivnih učinkov na telo in zdravje. Kot najbolj razširjen antioksidant, ga najdemo v različnih kozmetičnih, farmacevtskih in živilskih izdelkih. Med potrošniki se pojavlja vedno večji interes za naprednejše formulacije vitamina C v liposomalni obliki. Ta naj bi bila znatno učinkovitejša pri doseganju zdravilnih učinkov kot klasična oblika vitamina C v prašku, saj je absorbcija in biološka razpoložljivost v telesu boljša. Inkapsulirana učinkovina je z liposomsko ovojnico zaščitena pred zunanjimi vplivi in degradacijo, zato so liposomi učinkoviti dostavni sistemi zdravilnih učinkovin do tarčnih celic. Zanimalo me je, koliko vitamina C se dejansko zadrži v liposomih. Učinkovitost enkapsulacije vitamina C v liposomih sem preverila s kulometrično titracijo na primeru prehranskega dopolnila. Metoda je enostavna, hitra, zanesljiva in poceni. Izkaže se, da se izkoristki enkapsulacije v preiskovanem liposomalnem proizvodu vitamina C gibljejo okoli 15%.

Keywords

enkapsulacija;določanje vitamina C;kulometrična titracija;diplomska dela;

Data

Language: Slovenian
Year of publishing:
Typology: 2.11 - Undergraduate Thesis
Organization: UL FKKT - Faculty of Chemistry and Chemical Technology
Publisher: [Š. Zec]
UDC: 543.551.4:577.164.2(043.2)
COBISS: 218732803 Link will open in a new window
Views: 101
Downloads: 16
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Other data

Secondary language: English
Secondary title: Determining the encapsulation efficiency of liposomal vitamin C
Secondary abstract: Vitamin C is already well known due to its numerous positive effects on the body and health. As the most widespread antioxidant, it is found in various cosmetic, pharmaceutical and food products. There is an increasing interest among consumers in more advanced formulations of vitamin C in liposomal form. It is said to be significantly more effective in achieving medicinal effects than the classic powdered form of vitamin C, as absorption and biological availability in the body are better. The encapsulated active ingredient is protected from external influences and degradation by the liposomal membrane, making liposomes effective delivery systems for active ingredients to target cells. I was interested in how much vitamin C actually remains in the liposomes. I checked the efficiency of encapsulation of vitamin C in liposomes using a coulometric titration with the example of a dietary supplement. The method is simple, fast, reliable, and inexpensive. The results shows that the encapsulation efficiencies in the
Secondary keywords: vitamin C;liposomes;encapsulation;coulometry;Vitamin C;Liposomi;Univerzitetna in visokošolska dela;
Type (COBISS): Bachelor thesis/paper
Study programme: 1000373
Embargo end date (OpenAIRE): 1970-01-01
Thesis comment: Univ. v Ljubljani, Fak. za kemijo in kemijsko tehnologijo, UNI Kemija
Pages: 1 spletni vir (1 datoteka PDF (34 str.))
ID: 25225844