paving the way for personalized medicine
Abstract
Personalized medicine is promising a revolution for medicine and human biology in the 21st century. The scientific foundation for this revolution is accomplished by analyzing biological high-throughput data sets from genomics, transcriptomics, proteomics, and metabolomics. Currently, access to these data has been limited to either rather simple Web-based tools, which do not grant much insight or analysis by trained specialists, without firsthand involvement of the physician. Here, we present the novel Web-based tool “BioMiner,” which was developed within the scope of an international and interdisciplinary project (SYSTHER†) and gives access to a variety of high-throughput data sets. It provides the user with convenient tools to analyze complex cross-omics data sets and grants enhanced visualization abilities. BioMiner incorporates transcriptomic and cross-omics high-throughput data sets, with a focus on cancer. A public instance of BioMiner along with the database is available at http://systherDB.microdiscovery.de/, login and password: “systher”; a tutorial detailing the usage of BioMiner can be found in the Supplementary File.
Keywords
data mining;multiomics data integration;biomarker detection;pathway visualization;personalized medicine;cancer;
Data
Language: |
English |
Year of publishing: |
2015 |
Typology: |
1.01 - Original Scientific Article |
Organization: |
NIB - National Institute of Biology |
UDC: |
575.112 |
COBISS: |
3428687
|
ISSN: |
1176-9351 |
Views: |
17 |
Downloads: |
9 |
Average score: |
0 (0 votes) |
Metadata: |
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Other data
Secondary language: |
Unknown |
Type (COBISS): |
Not categorized |
Pages: |
str. 55-63 |
Issue: |
ǂVol. ǂ14 |
Chronology: |
2015 |
DOI: |
10.4137/CIN.S20910 |
ID: |
9142287 |