paving the way for personalized medicine
Chris Bauer (Author), Karol Stec (Author), Alexander Glintschert (Author), Kristina Gruden (Author), Christian Schichor (Author), Michal Or-Guil (Author), Joachim Selbig (Author), Johannes Schuchhardt (Author)

Abstract

Personalized medicine is promising a revolution for medicine and human biology in the 21st century. The scientific foundation for this revolution is accomplished by analyzing biological high-throughput data sets from genomics, transcriptomics, proteomics, and metabolomics. Currently, access to these data has been limited to either rather simple Web-based tools, which do not grant much insight or analysis by trained specialists, without firsthand involvement of the physician. Here, we present the novel Web-based tool “BioMiner,” which was developed within the scope of an international and interdisciplinary project (SYSTHER†) and gives access to a variety of high-throughput data sets. It provides the user with convenient tools to analyze complex cross-omics data sets and grants enhanced visualization abilities. BioMiner incorporates transcriptomic and cross-omics high-throughput data sets, with a focus on cancer. A public instance of BioMiner along with the database is available at http://systherDB.microdiscovery.de/, login and password: “systher”; a tutorial detailing the usage of BioMiner can be found in the Supplementary File.

Keywords

data mining;multiomics data integration;biomarker detection;pathway visualization;personalized medicine;cancer;

Data

Language: English
Year of publishing:
Typology: 1.01 - Original Scientific Article
Organization: NIB - National Institute of Biology
UDC: 575.112
COBISS: 3428687 Link will open in a new window
ISSN: 1176-9351
Views: 17
Downloads: 9
Average score: 0 (0 votes)
Metadata: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Other data

Secondary language: Unknown
Type (COBISS): Not categorized
Pages: str. 55-63
Issue: ǂVol. ǂ14
Chronology: 2015
DOI: 10.4137/CIN.S20910
ID: 9142287
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