paving the way for personalized medicine
Povzetek
Personalized medicine is promising a revolution for medicine and human biology in the 21st century. The scientific foundation for this revolution is accomplished by analyzing biological high-throughput data sets from genomics, transcriptomics, proteomics, and metabolomics. Currently, access to these data has been limited to either rather simple Web-based tools, which do not grant much insight or analysis by trained specialists, without firsthand involvement of the physician. Here, we present the novel Web-based tool “BioMiner,” which was developed within the scope of an international and interdisciplinary project (SYSTHER†) and gives access to a variety of high-throughput data sets. It provides the user with convenient tools to analyze complex cross-omics data sets and grants enhanced visualization abilities. BioMiner incorporates transcriptomic and cross-omics high-throughput data sets, with a focus on cancer. A public instance of BioMiner along with the database is available at http://systherDB.microdiscovery.de/, login and password: “systher”; a tutorial detailing the usage of BioMiner can be found in the Supplementary File.
Ključne besede
data mining;multiomics data integration;biomarker detection;pathway visualization;personalized medicine;cancer;
Podatki
Jezik: |
Angleški jezik |
Leto izida: |
2015 |
Tipologija: |
1.01 - Izvirni znanstveni članek |
Organizacija: |
NIB - Nacionalni inštitut za biologijo |
UDK: |
575.112 |
COBISS: |
3428687
|
ISSN: |
1176-9351 |
Št. ogledov: |
17 |
Št. prenosov: |
9 |
Ocena: |
0 (0 glasov) |
Metapodatki: |
|
Ostali podatki
Sekundarni jezik: |
Neznan jezik |
Vrsta dela (COBISS): |
Delo ni kategorizirano |
Strani: |
str. 55-63 |
Zvezek: |
ǂVol. ǂ14 |
Čas izdaje: |
2015 |
DOI: |
10.4137/CIN.S20910 |
ID: |
9142287 |