Gordana Jurak (Avtor), Jasna Bošnir (Avtor), Domagoj Đikić (Avtor), Ana Mojsović Ćuić (Avtor), Iva Pavlinić Prokurica (Avtor), Aleksandar Racz (Avtor), Tomislav Jukić (Avtor), David Štubljar (Avtor), Andrej Starc (Avtor)

Povzetek

Pesticides are chemicals used in agriculture to protect crops from pests. In addition to protection during cultivation, they are also used after harvesting to extend the shelf life of products. Postharvest control stands out, especially when it comes to products imported from distant countries, resulting in increased concentration of pesticides and risk to human health consuming such products. In this study, analyses of pesticide residues were performed on 200 samples of fruits and vegetables. Pesticide residues were identified and quantified in 30 out of 200 samples. Study results revealed imazalil to be the most frequently detected pesticide. Risk assessment was performed on the obtained results, and it was carried out separately for adults and for children under 6 years of age. Imazalil showed the highest ARfD percentage for adults (max% ARfD 251%), and these values were especially high on risk assessment for children, where they amounted up to max% ARfD 1087%. The study of imazalil impact was performed on 16 Swiss albino mice divided into two groups and 4 subgroups. Experimental group animals were treated with the corresponding NOAEL dose of imazalil (10 mg/kg) for 28 days. Body weight was measured before each pesticide application on a digital electronic Sartorius scale. Peripheral blood analysis was performed after 28-day animal exposure to pesticides. Animals were anesthetized, blood samples were obtained by cardiac puncture, and red blood cell (RBC) count, hemoglobin (Hb) concentration, and white blood cell (WBC) count were determined by standard hematological methods. The organs for determination of imazalil concentration were extracted immediately upon animal sacrifice and stored in a freezer at -80°C until analysis. Results show difference in gain weight, and an increase in WBC count was recorded in the experimental group as compared with a control group of animals. The highest imazalil levels were recorded in adipose tissue (45.2‰) which proves tendency to accumulate.

Ključne besede

human health;pesticides;imazalil;risk assessment;

Podatki

Jezik: Angleški jezik
Leto izida:
Tipologija: 1.01 - Izvirni znanstveni članek
Organizacija: UL ZF - Zdravstvena fakulteta
UDK: 614:632.95.024
COBISS: 67802883 Povezava se bo odprla v novem oknu
ISSN: 2314-5765
Št. ogledov: 327
Št. prenosov: 92
Ocena: 0 (0 glasov)
Metapodatki: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Ostali podatki

Sekundarni jezik: Angleški jezik
Sekundarne ključne besede: zdravje ljudi;pesticidi;imazalil;ocena tveganja;
Vrsta dela (COBISS): Članek v reviji
Strani: str. 1-8
Zvezek: ǂVol. ǂ2021
Čas izdaje: 2021
DOI: 10.1155/2021/9990219
ID: 13055806