Kaja Jeromel (Avtor), Mateja Primožič (Avtor), Vanja Kokol (Avtor), Željko Knez (Avtor), Maja Leitgeb (Avtor)

Povzetek

Biocompatible, mechanically stable, highly hydrophilic/swellable and safe antibacterial biomaterials are crucial for wound dressing and other applications in the health sector. Therefore, this study was conducted for the development of bacterial nanocellulose membranes, which were, for the frst time, enriched with bacteriostatic and bactericidal efective avocado seed extracts prepared by diferent extraction techniques (ultrasonic, Soxhlet, high pressure with supercritical carbon dioxide). First, the production process of bacterial nanocellulose membranes from Komagataeibacter hansenii bacteria was optimized related to the fermentation media composition and culture conditions, resulting in bacterial nanocellulose membranes with up to 83% crystallinity and 54.5 g/L yield. The morphological structure of the membranes was varied further by using air- and freeze-drying processes. The Soxhlet and high pressure with supercritical carbon dioxide avocado seed extracts with the most charge negative surface (-33 mV) and smallest hydrodynamic size (0.1 µm) thus resulted in 100% reduction of both Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus with up to log reduction of 2.56 and up to 100% bactericidal efficacy after 24 h of exposure, and at 14 mg/g of avocado seed extracts integrated in the bacterial nanocellulose membranes homogeneously. The high swelling (up to 600%) and water retention ability of avocado seed extracts enriched bacterial nanocellulose membranes, with a biocidal release up to 2.71 mg/mL, shows potential for antibacterial applications in the biomedicine, cosmetics, and pharmaceutical industries.

Ključne besede

nanoceluloza;avokadova semena;ekstrakcija;antibakterijske aktivnosti;bacterial nanocellulose membrane;avocado seed extracts;extraction;swelling;release;antibacterial activity;

Podatki

Jezik: Angleški jezik
Leto izida:
Tipologija: 1.01 - Izvirni znanstveni članek
Organizacija: UM FKKT - Fakulteta za kemijo in kemijsko tehnologijo
Založnik: Springer Link (Kluwer)
UDK: 620.3
COBISS: 191181059 Povezava se bo odprla v novem oknu
ISSN: 1572-882X
Št. ogledov: 70
Št. prenosov: 11
Ocena: 0 (0 glasov)
Metapodatki: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Ostali podatki

Sekundarni jezik: Slovenski jezik
Sekundarne ključne besede: nanoceluloza;avokadova semena;ekstrakcija;antibakterijske aktivnosti;
Vrsta dela (COBISS): Članek v reviji
Strani: str. 4305-4327
Zvezek: ǂVol. ǂ31
Čas izdaje: 2024
DOI: 10.1007/s10570-024-05839-3
ID: 24798325