Boštjan Korenjak (Avtor), Vladimira Erjavec (Avtor), Veronika Kralj-Iglič (Avtor)

Povzetek

Extracellular nanoparticles (EPs) in blood have been amply studied since their biological role was indicated more than 50 years ago. Among the various types of nano-sized blood constituents, the studies outlined lipoproteins, immune complexes and extracellular particles. Efforts have been invested to separate or separately assess different types of particles. Recently, much attention has been devoted to extracellular vesicles (EVs), however, experimental evidence indicates that the methods used for their harvesting and assessment importantly influence the content of the samples whereas the information on characteristics of the samples that could reflect the clinical status of the sample donor may be altered. Recent developments of the characterization methods point to the possibility of assessing nano-sized EPs directly in plasma and blood, thereby avoiding artefacts caused by processing. In this contribution, we consider the assessment of nano-sized EPs from blood and provide evidence supporting the direct assessment of EPs in plasma.

Ključne besede

extracellular particles from blood;extracellular particles from plasma;interferometric light microscopy;dynamic light scattering;

Podatki

Jezik: Angleški jezik
Leto izida:
Tipologija: 1.08 - Objavljeni znanstveni prispevek na konferenci
Organizacija: UL ZF - Zdravstvena fakulteta
UDK: 577
COBISS: 210329603 Povezava se bo odprla v novem oknu
Št. ogledov: 32
Št. prenosov: 6
Ocena: 0 (0 glasov)
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Ostali podatki

Vrsta dela (COBISS): Drugo
Strani: Str. 71-77
DOI: 10.55295/PSL.11.2024.8
ID: 25242010