Zdravljenje bolnikov s ploščatoceličnim karcinomom glave in vratu z obsevanjem in cetuksimabom

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Jezik:	Slovenski jezik
Leto izida:	2008
Tipologija:	1.04 - Strokovni članek
Organizacija:	OI - Onkološki inštitut Ljubljana
UDK:	616-006
COBISS:	701051
ISSN:	1408-1741
Matična publikacija:	Onkologija
Št. ogledov:	1949
Št. prenosov:	416
Ocena:	0 (0 glasov)
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Ostali podatki

Sekundarni jezik:	Angleški jezik
Sekundarni naslov:	Treatment of Patients with Squamous Cell Carcinoma of the Head and Neck with Concomitant Irradiation and Cetuximab
Sekundarni povzetek:	Contemporary management of locally and regionally advanced squamous cell carcinoma of the head and neck combines simultaneous application of radiotherapy and chemotherapy. With more comprehensive understanding of radiobiological principles of radiotherapy and recent developments in biological drug modeling and technology, more room was provided for improving some other areas of treatment. One of the new promising strategies in the treatment of head and neck carcinomas is the inhibition of epidermal growth factor receptor (EGFR) signaling using anti-EGFR monoclonal antibodies (e.g. cetuximab, Erbitux). In this article, we present the first two patients treated at the Institute of Oncology Ljubljana with the combination of irradiation and cetuximab and discuss theoretical background for the new treatment regime and other possible therapeutic indications for cetuximab in head and neck oncology.
URN:	URN:NBN:SI
Komentar vira:	BSDOCID143366;
Strani:	str. 84-88
Letnik:	ǂLetn. ǂ12
Zvezek:	ǂšt. ǂ2
Čas izdaje:	dec. 2008
ID:	10957600