Povzetek

Asthma is a severe and chronic disabling disease affecting more than 300 million people world-wide. While in the past few drugs for treatment of asthma were available, new treatment options are currently emerging which appear to be highly effective in certain subgroups of patients. Accordingly there is a need for biomarkers which allow selection of patients for refined and personalized treatment strategies. Recently, serological chip tests based on micro-arrayed allergen molecules and peptides derived from the most common rhinovirus strains have been developed which may discriminate two of the most common forms of asthma, i.e., allergen- and virus-triggered asthma. In this perspective we argue that classification of asthma patients according to these common trigger factors may open new possibilities for personalized management of asthma.

Ključne besede

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Podatki

Jezik: Angleški jezik
Leto izida:
Tipologija: 1.01 - Izvirni znanstveni članek
Založnik: Elsevier Inc.
UDK: 616-097
COBISS: 2048639089 Povezava se bo odprla v novem oknu
ISSN: 1097-6825
Št. ogledov: 1698
Št. prenosov: 599
Ocena: 0 (0 glasov)
Metapodatki: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Ostali podatki

Sekundarne ključne besede: sopenje;Allergy and immunology;Diagnosis;Therapy;Asthma;Signs and symptoms, respiratory;Rhinovirus;Allergens;Microarray analysis;Precision medicine;Alergija in imunologija;Diagnostika;Terapija;Astma;Respiratorni znaki in simptomi;Rinovirus;Alergeni;Analiza mikromrež;Personalizirana medicina;
Komentar vira: Nasl. z nasl. zaslona; Soavtorica iz Slovenije: Mihaela Zidarn; Opis vira z dne 28. 2. 2020;
Strani: str. 1529-1534
Letnik: ǂVol. ǂ145
Zvezek: ǂiss. ǂ6
Čas izdaje: Jun. 2020
DOI: 10.1016/j.jaci.2020.02.001
ID: 11928336