ǂa ǂthermal diffusivity study

Povzetek

The photothermal phenomenon has emerged as a potential tool for the nondestructive evaluation of thermal and optical properties of materials. Thermal analysis of drugs is an unavoidable part of preformulation study, as temperature variations can induce structural changes of the constituents of drugs. Techniques based on photothermal phenomena are highly sensitive, as only the absorbed radiation contributes to the signal. Periodic illumination and subsequent nonradiative de-excitation generate thermal lens signals of various types within and around the sample. Variation of thermal diffusivity with a concentration of the commonly used drug terbutaline is studied through the single-beam thermal lens technique. The ultraviolet–visible spectrum of the drug shows strong absorption around 500 nm, which suggests the possible wavelengths that can be used for the study. It is found that concentration of the drug in liquid form decides its thermal stability, as its thermal diffusivity varies with concentration. The study gives information about the optimum value for the concentration of the drug noted above for which the chance of thermal stability is high.

Ključne besede

thermal lens;thermal diffusivity;pharmacology;drugs;

Podatki

Jezik: Angleški jezik
Leto izida:
Tipologija: 1.01 - Izvirni znanstveni članek
Organizacija: UNG - Univerza v Novi Gorici
UDK: 54
COBISS: 113430275 Povezava se bo odprla v novem oknu
ISSN: 0740-3224
Št. ogledov: 483
Št. prenosov: 0
Ocena: 0 (0 glasov)
Metapodatki: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Ostali podatki

URN: URN:SI:UNG
Vrsta dela (COBISS): Delo ni kategorizirano
Strani: str. 1662-1665
Letnik: ǂVol. ǂ35
Zvezek: ǂiss. ǂ7
Čas izdaje: 2018
DOI: 10.1364/JOSAB.35.001662
ID: 15786699
Priporočena dela:
, ǂa ǂthermal diffusivity study
, ǂa ǂcomparison between conventional and self-mixing schemes
, thermal lens microscopy
, characterization and optimization