ǂan ǂoptimized scientific and regulatory framework for their characterization and risk analysis
Nuria Fontdevila Pareta (Avtor), Maryam Khalili (Avtor), Ayoub Maachi (Avtor), Mark Paul Selda Rivarez (Avtor), Johan Rollin (Avtor), Ferran Salavert Pamblanco (Avtor), Coline Temple (Avtor), Miguel A. Aranda (Avtor), Denis Kutnjak (Avtor), Maja Ravnikar (Avtor)

Povzetek

The advances in high-throughput sequencing (HTS) technologies and bioinformatic tools have provided new opportunities for virus and viroid discovery and diagnostics. Hence, new sequences of viral origin are being discovered and published at a previously unseen rate. Therefore, a collective effort was undertaken to write and propose a framework for prioritizing the biological characterization steps needed after discovering a new plant virus to evaluate its impact at different levels. Even though the proposed approach was widely used, a revision of these guidelines was prepared to consider virus discovery and characterization trends and integrate novel approaches and tools recently published or under development. This updated framework is more adapted to the current rate of virus discovery and provides an improved prioritization for filling knowledge and data gaps. It consists of four distinct steps adapted to include a multi-stakeholder feedback loop. Key improvements include better prioritization and organization of the various steps, earlier data sharing among researchers and involved stakeholders, public database screening, and exploitation of genomic information to predict biological properties.

Ključne besede

rastlinski virusi in viroidi;sekvenciranje;zdravje rastlin;virusna bolezen;plant viruses and viroids;high throughput sequencing (HTS);biological characterization;plant health;regulatory agencies;Pest Risk Analysis (PRA);virus disease;

Podatki

Jezik: Angleški jezik
Leto izida:
Tipologija: 1.01 - Izvirni znanstveni članek
Organizacija: NIB - Nacionalni inštitut za biologijo
UDK: 632
COBISS: 155443459 Povezava se bo odprla v novem oknu
ISSN: 1664-302X
Št. ogledov: 20
Št. prenosov: 9
Ocena: 0 (0 glasov)
Metapodatki: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Ostali podatki

Sekundarni jezik: Slovenski jezik
Sekundarne ključne besede: rastlinski virusi in viroidi;sekvenciranje;zdravje rastlin;virusna bolezen;
Komentar vira: Soavtorji: Maryam Khalili, Ayoub Maachi, Mark Paul S. Rivarez, Johan Rollin, Ferran Salavert, Coline Temple, Miguel A. Aranda, Neil Boonham, Marleen Botermans, Thierry Candresse, Adrian Fox, Yolanda Hernando, Denis Kutnjak, Armelle Marais, Françoise Petter, Maja Ravnikar, Ilhem Selmi, Rachid Tahzima, Charlotte Trontin, Thierry Wetzel and Sebastien Massart; Nasl. z nasl. zaslona; Opis vira z dne 13. 6. 2023;
Strani: str. 1-13
Letnik: ǂVol. ǂ14
Zvezek: ǂart. ǂ1181562
Čas izdaje: May 2023
DOI: 10.3389/fmicb.2023.1181562
ID: 24512629