Editorial

brain cancer pathogenesis and data integration

Andrea Comba (Avtor), Xinzhong Li (Avtor), Barbara Breznik (Avtor)

Povzetek

Brain tumors are one of the most aggressive malignancies in humans. They can be classified as primary tumors, which arise in the brain, or secondary tumors, which arise elsewhere in the body and initially metastaze the brain. The morbidity and mortality of brain tumors is one of the highest among cancers (Siegel et al., 2023). Of particular concern is that mortality and incidence of brain tumors are increasing, especially in the population under 44 years of age. Brain tumor mortality in this population is 13.4%. For example, primary brain tumors are the most common cancer in children and the leading cause of death in pediatric cancer patients (Gould, 2018). Considering the low survival rate of adult and pediatric brain tumor patients and the detrimental impact on patient quality of life, economic costs, and mortality rates, there is an urgent need to develop more effective therapeutic approaches. Despite major research efforts, there are currently no effective treatment modalities or prevention strategies that would significantly improve the quality of life and disease outcome of brain tumor patients.

Ključne besede

brain tumor;data integration;therapeutic resistance;biomarkers;liquid biopsies;

Podatki

Jezik:	Angleški jezik
Leto izida:	2023
Tipologija:	1.03 - Kratki znanstveni prispevek
Organizacija:	NIB - Nacionalni inštitut za biologijo
UDK:	616-006
COBISS:	169559043
ISSN:	1664-8021
Št. ogledov:	15
Št. prenosov:	5
Ocena:	0 (0 glasov)
Metapodatki:

Ostali podatki

Sekundarni jezik:	Slovenski jezik
Sekundarne ključne besede:	možganski tumorji;integracija podatkov;biološki označevalci;biomarkerji;rak;onkologija;
Komentar vira:	Nasl. z nasl. zaslona; Opis vira z dne 24. 10. 2023;
Strani:	str. 1-2
Letnik:	ǂVol. ǂ14
Zvezek:	ǂ[article no.] ǂ1298285
Čas izdaje:	Oct. 2023
DOI:	10.3389/fgene.2023.1298285
ID:	24669956