Roman Kranvogl (Avtor), Jure Knez (Avtor), Alen Miuc (Avtor), Ernest Vončina (Avtor), Darinka Brodnjak-Vončina (Avtor), Veljko Vlaisavljević (Avtor)

Povzetek

A GC-MS method was successfully applied to measure simultaneously the concentrations of endocrine disrupting compounds (5 dialkyl phthalates, 9 phthalate monoesters, 3 alkylphenols and bisphenol A) in 136 male urine samples. In the present study the method was validated and concentrations of EDCs were determined. The results were compared with results from other studies. Correlations between endocrine disrupting compounds and also correlations of endocrine disrupting compounds with two semen quality parameters are presented and evaluated. Significant positive correlations were found between almost all the endocrine disrupting compounds. The parameter sum of DEHP (SUM DEHP) was positively correlated to all the endocrine disrupting compounds but negatively to two semen quality parameters. Negative correlations between the endocrine disrupting compounds and the semen quality parameters could indicate that endocrine disrupting compounds could cause reproductive problems by decreasing the semen count and quality. This research will have helped to evaluate human exposure to endocrine disrupting compounds.

Ključne besede

endocrine disrupting compounds;fertility;phthalates;bisphenol A;alkylphenols;human urine;

Podatki

Jezik: Angleški jezik
Leto izida:
Tipologija: 1.01 - Izvirni znanstveni članek
Organizacija: UM FKKT - Fakulteta za kemijo in kemijsko tehnologijo
UDK: 543.21:663.2
COBISS: 17710102 Povezava se bo odprla v novem oknu
ISSN: 1318-0207
Št. ogledov: 1239
Št. prenosov: 98
Ocena: 0 (0 glasov)
Metapodatki: JSON JSON-RDF JSON-LD TURTLE N-TRIPLES XML RDFA MICRODATA DC-XML DC-RDF RDF

Ostali podatki

Sekundarni jezik: Slovenski jezik
Sekundarni povzetek: S plinsko kromatografijo in masno spektrometrijo smo simultano določali koncentracije endokrinih motilcev (5 dialkil ftalatov, 9 monoalkil ftalatov, 3 alkilfenole in bisfenol A) v 136 vzorcih moških urinov. Rezultate smo primerjali z ostalimi študijami. Ovrednotili smo korelacije med endokrinimi motilci in korelacije med endokrinimi motilci ter parametri semena. Signifikantne pozitivne korelacije obstajajo med skoraj vsemi endokrinimi motilci. Parameter vsote DEHP (SUM DEHP) pozitivno korelira z vsemi endokrinimi motilci in negativno s paramateri kvalitete semena. Negativne korelacije med endokrinimi motilci ter parametri kvalitete semena nakazujejo, da lahko povzročajo probleme s plodnostjo z zmanjšanjem koncentracije in gibljivosti semena. Raziskava bo pripomogla k ovrednotenju izpostavljenosti ljudi vplivom endokrinih motilcev.
Sekundarne ključne besede: analizna kemija;endokrini motilci;ftalati;urin;plinska kromatografija;kemijska analiza;
URN: URN:NBN:SI
Vrsta dela (COBISS): Znanstveno delo
Strani: str. 110-120
Letnik: ǂVol. ǂ61
Zvezek: ǂno. ǂ1
Čas izdaje: 2014
ID: 9101641