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Št. zadetkov: 4
Adhesion and stiffness of detached breast cancer cells in vitro
Špela Zemljič Jokhadar, Špela Zemljič Jokhadar, Gašper Kokot, Mojca Pavlin, Jure Derganc
Izvirni znanstveni članek
Oznake: metastatic potential;adhesion to epithelial cells;optical tweezers;
Metastatic cancer cells can overcome detachment-induced cell death and can proliferate in anchorage-independent conditions. A recent study revealed that a co-treatment with two drugs that interfere with cell metabolism, metformin and 2-deoxy-D-glucose, promotes detachment of viable MDA-MB-231 breast ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
ǂThe ǂpore-forming action of polyenes
Luka Kristanc, Bojan Božič, Špela Zemljič Jokhadar, Marija Sollner Dolenc, Gregor Gomišček
Pregledni znanstveni članek
Oznake: polyenes;sterols;pore forming;tension pore;osmotic stress;
The incidence of resistant fungal pathogens has been increasing, especially in immuno-compromised people. As such, considerable research has been focused on discovering anti-fungal agents with new mechanisms of action and on optimizing the use of existing agents. In this context, interest in the pol ...
Leto: 2019 Vir: Fakulteta za farmacijo (UL FFA)
Induced pluripotent stem cell (iPSC) line MLi-004A derived from a patient with recessive dystrophic epidermolysis bullosa (RDEB)
Sandra Ropret, Jakob Jeriha, Tjaša Sorčan, Marija Rogar, Špela Zemljič Jokhadar, John A. McGrath, Dusko Ilic, Mirjana Liović
Izvirni znanstveni članek
Oznake: matične celice;epidermoliza;kolagen VII;stem cell;epidermolysis;collagen VII;
We have generated MLi004-A, a new induced pluripotent stem cell (iPSC) line derived from skin fibroblasts of a female patient with recessive dystrophic epidermolysis bullosa (RDEB). This iPSC line may be used as a model system for studies on skin integrity, the extracellular matrix and skin barrier ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Keratin dynamics and spatial distribution in wild-type and K14 R125P mutant cells - a computational model
Marcos Gouveia, Hiroko Ikeshima-Kataoka, Špela Zemljič Jokhadar, Marko Vidak, Biljana Stojković, Jure Derganc, Rui Travasso, Mirjana Liović
Izvirni znanstveni članek
Oznake: keratin;epidermoliza bullosa simplex;mutacija;epidermolysis bullosa simplex;mutation;
Keratins are one of the most abundant proteins in epithelial cells. They form a cytoskeletal filament network whose structural organization seriously conditions its function. Dynamic keratin particles and aggregates are often observed at the periphery of mutant keratinocytes related to the hereditar ...
Leto: 2020 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 4
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