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Št. zadetkov: 3
Real-world testing practices, treatment patterns and clinical outcomes in patients from Central Eastern Europe with EGFR-mutated advanced non-small cell lung cancer
Urška Janžič, Nina Turnšek, Mircea Dediu, Ivan Shterev Donev, Roxana Lupu, Gabriela Teodorescu, Tudor Ciuleanu, Adam Płużański, Adam Płużański
Izvirni znanstveni članek
Oznake: klinične študije;raziskava REFLECT;receptor epidermalnega rastnega faktorja;rak pljuč;real-world study;REFLECT study;epidermal growth factor receptor;lung cancer;
The targeted therapy with tyrosine kinase inhibitors (TKIs) against the epidermal growth factor receptor mutation (EGFRm) in advanced non-small cell lung cancer (NSCLC) changed the treatment paradigm. REFLECT study (NCT04031898) explored EGFR/T790M testing and treatment patterns in EGFRm NSCLC patie ...
Leto: 2022 Vir: Onkološki inštitut Ljubljana (OI)
Real-world experience in treatment of patients with non-small-cell lung cancer with BRAF or cMET exon 14 skipping mutations
Urška Janžič, Walid Shalata, Katarzyna Szymczak, Rafal Dziadziuszko, Marko Jakopović, Giannis Mountzios, Adam Płużański, António Araújo, Andriani Charpidou, Abed Agbarya
Izvirni znanstveni članek
Oznake: nedrobnocelični pljučni rak;mutacija BRAF V600;podatki iz resničnega življenja;tarčna terapija;zdravljenje prvega reda;non-small-cell lung cancer;BRAF V600 mutation;cMET exon 14 skipping mutation;real-world data;targeted therapy;first-line therapy;
BRAF and cMET exon 14 skipping are rare mutations of NSCLC. The treatment sequence in these cases for the first and second line is not clear. An international registry was created for patients with advanced NSCLC harboring BRAF or cMET exon 14 skipping mutations, diagnosed from January 2017 to June ...
Leto: 2023 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Treatment patterns, testing practices, and outcomes in the pre-FLAURA era for patients with EGFR mutation-positive advanced NSCLC
Alfredo Addeo, Maximilian J Hochmair, Urška Janžič, Elizabeth Dudnik, Andriani Charpidou, Adam Płużański, Tudor Ciuleanu, Ivan Shterev Donev, Judith Elbaz, Jørgen Aarøe, René Ott, Nir Peled
Izvirni znanstveni članek
Oznake: napredovali nedrobnocelinčni karcinom pljuč;podatki iz resničnega življenja;srednja Evropa;advanced non-small cell lung cancer;real-world data;Central Europe;
Background. Immunotherapy with immune checkpoint inhibitors (ICIs) recently became the standard treatment for patients with advanced non-small cell lung cancer (NSCLC). Here, we present the first results of a real-world observational study on the effectiveness of ICI monotherapy in patients with adv ...
Leto: 2021 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Št. zadetkov: 3
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