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Št. zadetkov: 3
Non-dilated left ventricular cardiomyopathy with arrhythmias is commonly caused by the nonsense variant DSP:c.3793G>T in Slovenian patients
Nina Vodnjov, Anja Zupan, Aleš Maver, Ajda Dolinšek, Borut Peterlin, Karin Writzl
Izvirni znanstveni članek
Oznake: sarrhythmogenic non-dilated left ventricular cardiomyopathy;cardiogenetic;cardiology;DSP;DSP:c.3793G>T;founder;
DSP-cardiomyopathy has recently been recognised as a specific type of cardiomyopathy. Using an in-house Mendelian disease registry, we aimed to identify probands with likely pathogenic or pathogenic DSP variants. We detected these variants in 4.8% and 77.8% of genotype-positive probands referred for ...
Leto: 2024 Vir: Biotehniška fakulteta (UL BF)
Aktivacija vzorčno prepoznavnih senzorjev po genskem elektroprenosu plazmida z zapisom za interlevkin-12
Ajda Vrabič, Tanja Dolinšek, Gregor Serša, Maša Bošnjak, Maja Čemažar
Objavljeni povzetek znanstvenega prispevka na konferenci
Oznake: miši;obsevanje;gensko zdravljenje;
Leto: 2023 Vir: Onkološki inštitut Ljubljana (OI)
Expression of inducible damage-associated molecular patterns after interleukin-12 gene electrotransfer in mouse melanoma and colorectal cell lines
Ajda Vrabič, Maša Bošnjak, Tanja Dolinšek, Simon Buček, Gregor Serša, Maja Čemažar
Izvirni znanstveni članek
Oznake: elektroprenos genov;citokini;interlevkin-12;gene electrotransfer;cytokine;interleukin-12;
Interleukin-12 (IL-12) has demonstrated potent antitumor effects by activating natural killer (NK) and T cells, but its systemic administration poses challenges due to toxicity. This study investigated gene electrotransfer (GET) as a localized delivery method for IL-12 plasmids in B16F10 and CT26 tu ...
Leto: 2025 Vir: Onkološki inštitut Ljubljana (OI)
Št. zadetkov: 3
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