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Št. zadetkov: 2
Ibogaine-mediated ROS/antioxidant elevation in isolated rat uterus is β-adrenergic receptors and KATP channels mediated
Nikola Tatalović, Teodora Vidonja-Uzelac, Zorana Oreščanin-Dušić, Aleksandra Nikolić-Kokić, Mara Bresjanac, Duško Blagojević, Duško Blagojević
Izvirni znanstveni članek
Oznake: ibogaine;KATP channels;glibenclamide;β-adrenergic receptors;propranolol;antioxidative enzymes;superoxide dismutase;catalase;uterus;contractility;
Ibogaine effects are mediated by cellular receptors, ATP depletion followed by ROS production and antioxidant enzyme activity elevation in a dose and time dependent manner. Since the role of KATP channels and β-adrenoceptors in ROS cellular circuit was established here we explored their role in ibog ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Ibogaine has sex-specific plasma bioavailability, histopathological and redox/antioxidant effects in rat liver and kidneys
Nikola Tatalović, Teodora Vidonja-Uzelac, Milica Mijović, Gordana Koželj, Aleksandra Nikolić-Kokić, Zorana Oreščanin-Dušić, Mara Bresjanac, Duško Blagojević
Izvirni znanstveni članek
Oznake: noribogaine;erythrocytes;liver;
Ibogaine induces rapid changes in cellular energetics followed by the elevation of antiox- idant activities. As shown earlier in male rats, ibogaine treatment with both 1 and 20 mg/kg b.w. per os led to significant glycogenolytic activity in the liver. In this work, female rats treated with the same ...
Leto: 2022 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 2
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