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Dissecting the role of REEP1 in preventing Tau-mediated neurodegeneration in a D. melanogaster Alzheimer's disease model
Alessio Guglielmi, Fabian M. Feiguin
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Oznake: Alzheimer disease;amyloid precursor protein;central nervous system;drosophila melanogaster;hereditary spastic paraplegia;microtubule;Lewy's neurite;microtubule associated protein;microtubule/s;microtubule binding domain;neurofibrillary tangle;dissertation;
Tau is natively an unfolded protein that promotes the assembly and the stability of the axonal microtubules in the central nervous system. Increased formation of Tau protein aggregates has been causatively implicated in several neurodegenerative diseases called tauopathies. In the present stud ...
Leto: 2019 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
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