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Izvirni znanstveni članek
Oznake: amphetamine;anhedonia;morphine;ultrasonic vocalizations;Wistar-Kyoto rat;
The Wistar-Kyoto rat strain (WKY) is a model for treatment-resistant depression, exhibiting behaviors indicative of anhedonia. Although anhedonia is measured using the sucrose preference test (SPT), 50-kHz ultrasonic vocalizations (USVs) hold promise as a complementary assessment tool. This study ai ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake: antidepressant;depression;enantiomers;ketamine;model of depression;psychomotor effects;Wistar-Kyoto;
Ketamine, a fast-acting antidepressant, is a racemic mixture, composed of equal amounts of R- and S-ketamine. Preclinical studies are comparing them to better understand their role in therapeutic and undesirable effects. An important research gap is that studies do not use long clinically relevant p ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 2
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