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Št. zadetkov: 14
Emerging treatment strategies for polycystic ovary syndrome women with obesity
Mojca Jensterle Sever, Manfredi Rizzo, Andrej Janež, Andrej Janež
Kratki znanstveni prispevek
Oznake: polycystic ovary syndrome;obesity;glucagon-like peptide-1 receptor agonists;
Leto: 2024 Vir: Medicinska fakulteta (UL MF)
Semaglutide delays 4-hour gastric emptying in women with PCOS and obesity
Mojca Jensterle Sever, Simona Ferjan, Luka Ležaič, Aljaž Sočan, Katja Goričar, Katja Zaletel, Andrej Janež, Andrej Janež
Izvirni znanstveni članek
Oznake: PCOS;debelost;semaglutid;obesity;semaglutide;
Context: Semaglutide could contribute to reduced energy intake and weight loss by delaying gastric emptying (GE). However, the evidence for notable effects of semaglutide is inconclusive and compromised by the use of indirect methodology. Objective: to evaluate the effect of once-weekly subcutaneous ...
Leto: 2023 Vir: Medicinska fakulteta (UL MF)
Metabolični sindrom včeraj, danes, jutri
Andrej Janež
Poljudni članek
Oznake:
Metabolični sindrom včeraj, danes, jutri
Leto: 2007 Vir: Centralna tehniška knjižnica Univerze v Ljubljani (CTK)
ǂThe ǂimpact of degradation inhibitor of glucagon like polypeptide 1 on body weight and beta-cell function in obese women with polycystic ovarian syndrome
Simona Ferjan, Mojca Jensterle Sever, Andrej Janež
Doktorska disertacija
Oznake: PCOS;prediabetes;GLP-1 response;DPP-4 inhibitor;sitagliptin;weight maintenance;GLP-1 receptor agonist;liraglutide;
Obesity is highly prevalent in polycystic ovary syndrome (PCOS). It worsens reproductive and metabolic abnormalities of the syndrome, in particular insulin resistance (IR), Weight manegment and decreasing IR with lifestyle modification and metformin are well-addressed targets in this population, yet ...
Leto: 2018 Vir: Medicinska fakulteta (UL MF)
Glucagon-like peptide 1 and taste perception
Mojca Jensterle Sever, Manfredi Rizzo, Andrej Janež
Pregledni znanstveni članek
Oznake: glukagonu podoben peptid 1 (GLP-1);okus;jezik;debelost;sladko;glucagon-like peptide 1 (GLP-1);taste;tongue;obesity;sweet;
Preclinical studies provided some important insights into the action of glucagon-like peptide 1 (GLP-1) in taste perception. This review examines the literature to uncover some molecular mechanisms and connections between GLP-1 and the gustatory coding. Local GLP-1 production in the taste bud cells, ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Učinki dolgoletnega zdravljenja z metforminom na klinične, presnovne in hormonske kazalce pri bolnicah s sindromom policističnih jajčnikov in povečanim presnovnim tveganjem
Nika Aleksandra Kravos, Andrej Janež, Mojca Jensterle Sever
Doktorska disertacija
Oznake: endokrinologija;
Uvod: Sindrom policističnih jajčnikov (angl. polycystic ovary syndrome – PCOS) je najpogo-stejša endokrina motnja pri ženskah v rodni dobi. Značilnosti PCOS so hiperandrogenizem, kronične anovulacije in presnovne motnje, med katerimi je poglavitna insulinska rezistenca. Temeljno zdravilo za vse boln ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Genetic variability in antioxidative and inflammatory pathways modifies the risk for PCOS and influences metabolic profile of the syndrome
Rok Herman, Mojca Jensterle Sever, Andrej Janež, Katja Goričar, Vita Dolžan
Izvirni znanstveni članek
Oznake: sindrom policističnih jajčnikov;genetska variabilnost;oksidativni stres;polycystic ovary syndrome;genetic variability;oxidative stress;
Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder of multifactorial etiopathology likely to involve the interactions between genetics and lifestyle. Chronic inflammation and oxidative stress (OS) may participate in the pathophysiology of the syndrome. The question of the ...
Leto: 2020 Vir: Medicinska fakulteta (UL MF)
In vivo experimental study of noninvasive insulin microinjection through hollow si microneedle array
Drago Resnik, Matej Možek, Borut Pečar, Andrej Janež, Vilma Urbančič-Rovan, Ciprian Iliescu, Danilo Vrtačnik
Izvirni znanstveni članek
Oznake: votla Si mikronaična matrika;mikroinjektiranje;in vivo dajanje insulina;polje votlih Si mikrokonic;mikroinjiciranje;doziranje inzulina in-vivo;izkoristek vnosa;hollow Si microneedle array;microinjection;in vivo insulin delivery;drug transfer efficiency;
An experimental study of in vivo insulin delivery through microinjection by using hollow silicon microneedle array is presented. A case study was carried out on a healthy human subject in vivo to determine the influence of delivery parameters on drug transfer efficiency. As a microinjection device, ...
Leto: 2018 Vir: Fakulteta za elektrotehniko (UL FE)
Metformin and insulin resistance
Rok Herman, Nika Aleksandra Kravos, Mojca Jensterle Sever, Andrej Janež, Vita Dolžan, Vita Dolžan
Pregledni znanstveni članek
Oznake: metformin;insulin resistance;glucose transport;
Metformin is the most commonly used treatment to increase insulin sensitivity in insulin-resistant (IR) conditions such as diabetes, prediabetes, polycystic ovary syndrome, and obesity. There is a well-documented correlation between glucose transporter 4 (GLUT4) expression and the level of IR. There ...
Leto: 2022 Vir: Medicinska fakulteta (UL MF)
Skeletal-muscle-derived mesenchymal stem/stromal cells from patients with osteoarthritis show superior biological properties compared to bone-derived cells
Klemen Čamernik, Anže Mihelič, Rene Mihalič, Darja Marolt, Andrej Janež, Rihard Trebše, Janja Marc, Janja Zupan
Izvirni znanstveni članek
Oznake: mesenchymal stem/stromal cells;osteoarthritis;bone;muscle;CD271;
Mesenchymal stem/stromal cells (MSCs) are being exploited for patient-derived stem-cell therapies. As the biological properties of MSCs derived from skeletal muscle of osteoarthritis patients are poorly understood, the aim of this study was to compare muscle MSCs with well-recognized bone and bone m ...
Leto: 2019 Vir: Fakulteta za farmacijo (UL FFA)
Št. zadetkov: 14
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