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Št. zadetkov: 2
Real-world use of complement inhibitors for haemolytic uraemic syndrome
Aleksandra Vujović, Anne-Laure Sellier-Leclerc, Maria Cristina Mancuso, Olivia Boyer, Atif Awan, Antonio Gargiulo, Tanja Kersnik-Levart
Izvirni znanstveni članek
Oznake: haemolytic uraemic syndrome;complement inhibitor;treatment discontinuation;post-withdrawal relapse;European Rare Kidney Disease Registry;
Background: Although terminal complement inhibitors transformed the prognosis of atypical haemolytic uraemic syndrome (aHUS) from dismal to favourable, treatment approaches vary due to the intermittent disease nature and high costs. Occasionally, complement inhibition is applied in infectious (i)HUS ...
Leto: 2025 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Antimeningococcal protection in patients receiving terminal complement inhibitors
Aleksandra Vujović, Franz Schaefer, Anne-Laure Sellier-Leclerc, Mattia Parolin, Víctor Pérez-Beltrán, Jonas Hofstetter, Olivia Boyer, Tanja Kersnik-Levart
Izvirni znanstveni članek
Oznake: antibiotic prophylaxis;antimeningococcal protection;antimeningococcal vaccination;atypical hemolytic uremic syndrome;complement inhibitors;meningococcal infection;
Introduction: C5 inhibitor (C5i) therapy markedly increases susceptibility to invasive meningococcal disease (IMD) by blocking the terminal complement pathway essential for defense against Neisseria meningitidis. Vaccination is recommended for all recipients, yet breakthrough infections persist. Ant ...
Leto: 2026 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Št. zadetkov: 2
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