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Limited predictive value of PD-L1 TPS for pathological response in NSCLC is not attributable to interobserver variability
Konrad Steinestel, Lena-Maria Löwer-Kiem, Francesca Ambrosi, Anne-Sophie Becker, Hanibal Bohnenberger, Konstantin Bräutigam, Gerardo Cazzato, Esther Conde, Andreea-Raluca Cozac-Szőke, Daniel Curto, Jan-Olof Dahlberg, João Martins Gama, Alessandro Gambella, Georg Hutarew, Fernando Lopez-Rios, Stefano Lucà, Francesca Lunardi, Christian Matek, Christian Meyer, Gheorghe-Emilian Olteanu, Helmut H. Popper, Anja C Roden, Menelaos G Samaras, Kristijan Skok, David Suster, Annikka Weissferdt, Jozef Zustin, Christiane Kümpers, Felix Elsner
Izvirni znanstveni članek
Oznake: non-small cell lung cancer (NSCLC);PD-L1;tumor proportion score (TPS);residual viable tumor (RVT);neoadjuvant chemoimmunotherapy;interobserver variability;
Background PD-L1 tumor proportion score (TPS) is used to guide immunotherapy in non-small cell lung cancer (NSCLC), yet its ability to predict pathological response in the neoadjuvant setting remains limited. Methods Thirty pathologists from 11 countries independently assessed PD-L1 TPS in pre-treat ...
Leto: 2026 Vir: Medicinska fakulteta (UM MF)
Št. zadetkov: 1
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