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Neuroleptics were discovered by chance in 1950. Since then, a substantial bodyof clinical experiences has been collected. The understanding of mechanisms of their action stimulated the development of new theories about the causes of mental disorders. Neuroleptics are symptomatic drugs, because they ...

Neuroleptic malignant syndrome is rare, but potentially fatal complication of treatment with neuroleptics and other psychotropic drugs. The authors review the relevant literature and discuss the incidence and possible etiology of this disorder. Most studies have confirmed the role of dopamine and ot ...