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Št. zadetkov: 2
Computational design and development of benzodioxane-benzamides as potent inhibitors of FtsZ by exploring the hydrophobic subpocket
Valentina Straniero, Victor Sebastián-Pérez, Lorenzo Suigo, William Margolin, Andrea Casiraghi, Martina Hrast, Carlo Zanotto, Irena Zdovc, Antonia Radaelli, Ermanno Valoti
Izvirni znanstveni članek
Oznake: Veterinarska medicina;
Multidrug resistant Staphylococcus aureus is a severe threat, responsible for most of the nosocomial infections globally. This resistant strain is associated with a 64% increase in death compared to the antibiotic-susceptible strain. The prokaryotic protein FtsZ and the cell division cycle have been ...
Leto: 2021 Vir: Fakulteta za farmacijo (UL FFA)
Benzamide derivatives targeting the cell division protein FtsZ
Valentina Straniero, Lorenzo Suigo, Andrea Casiraghi, Victor Sebastián-Pérez, Martina Hrast, Carlo Zanotto, Irena Zdovc, Carlo De Giuli Morghen, Antonia Radaelli, Ermanno Valoti
Izvirni znanstveni članek
Oznake: Veterinarska medicina;
Filamentous temperature-sensitive Z (FtsZ) is a prokaryotic protein with an essential role in the bacterial cell division process. It is widely conserved and expressed in both Gram-positive and Gram-negative strains. In the last decade, several research groups have pointed out molecules able to targ ...
Leto: 2020 Vir: Veterinarska fakulteta (UL VF)
Št. zadetkov: 2
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