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UV-radiation and MC1R germline mutations are risk factors for the development of conventional and spitzoid melanomas in children and adolescents
Alexandra Liebmann, Jakob Admard, Sorin Armeanu-Ebinger, Hannah Wild, Michael Abele, Axel Gschwind, Olga Seibel-Kelemen, Christian Seitz, Irina Bonzheim, Olaf Rieß, Maja Česen
Izvirni znanstveni članek
Oznake: paediatric melanoma;exome sequencing;tumour-normal sequencing;rare paediatric tumours;
Background: Genomic characterisation has led to an improved understanding of adult melanoma. However, the aetiology of melanoma in children is still unclear and identifying the correct diagnosis and therapeutic strategies remains challenging. Methods: Exome sequencing of matched tumour-normal pairs ...
Leto: 2023 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
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