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Clinical pharmacogenetic models of treatment response to methotrexate monotherapy in Slovenian and Serbian rheumatoid arthritis patients
Barbara Jenko, Matija Tomšič, Biljana Jekić, Vera Milić, Vita Dolžan, Sonja Praprotnik
Izvirni znanstveni članek
Oznake: rheumatoid arthritis;methotrexate;pharmacogenetics;polymorphism;predictive model;
Objectives: Methotrexate (MTX) is the first line treatment for rheumatoid arthritis (RA), but nevertheless 30% of patients experience MTX inefficacy. Our aim was to develop a clinical pharmacogenetic model to predict which RA patients will not respond to MTX monotherapy. We also assessed whether thi ...
Leto: 2018 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 1
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