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Building and applying quantitative adverse outcome pathway models for chemical hazard and risk assessment
Edward J. Perkins, Roman Ashauer, Lyle Burgoon, Rory Conolly, Brigitte Landesmann, Cameron Mackay, Cheryl A. Murphy, Nathan Pollesch, James R. Wheeler, Anže Županič, Stefan Scholz
Pregledni znanstveni članek
Oznake: Quantitative Adverse Outcome pathways;TKTD modelling;alternatives to animal testing;predictive toxicology;species extrapolation;prioritization of chemicals;
An important goal in toxicology is the development of new ways to increase the speed, accuracy, and applicability of chemical hazard and risk assessment approaches. A promising route is the integration of in vitro assays with biological pathway information. We examined how the adverse outcome pathwa ...
Leto: 2019 Vir: Nacionalni inštitut za biologijo (NIB)
Št. zadetkov: 1
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