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Št. zadetkov: 4
ǂThe ǂeffect of serum withdrawal on the protein profile of quiescent human dermal fibroblasts in primary cell culture
Federica Boraldi, Giulia Annovi, Chiara Paolinelli DeVincenzi, Roberta Tiozzo, Daniela Quaglino
Izvirni znanstveni članek
Oznake: dermal fibroblasts;primary cell culture;ROS production;serum withdrawal;
The effect of serum deprivation on proliferating cells is well known, in contrast its role on primary cell cultures, at confluence, has not been deeply investigated. Therefore, in order to explore the response of quiescent cells to serum deprivation, ubiquitous mesenchymal cells, as normal human ...
Leto: 2008 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Matrix Gla protein is involved in elastic fiber calcification in the dermis of pseudoxanthoma elasticum patients
Dealba Gheduzzi, Federica Boraldi, Giulia Annovi, Chiara Paolinelli DeVincenzi, Leon J. Schurgers, Cees Vermeer, Daniela Quaglino, Ivonne Pasquali Ronchetti
Izvirni znanstveni članek
Oznake: calcification;dermal fibroblast;elastic fiber;human skin;MGP;pseudoxanthoma elasticum;
Mature MGP (Matrix g-carboxyglutamic acid protein) is known to inhibit soft connective tissues calcification. We investigated its possible involvement in pseudoxanthoma elasticum (PXE), a genetic disorder whose clinical manifestations are due to mineralization of elastic fibers. PXE patients have ...
Leto: 2007 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Ectopic calcification in [beta]-thalassemia patients is associated with increased oxidative stress and lower MGP carboxylation
Federica Boraldi, Maria Garcia-Fernandez, Chiara Paolinelli DeVincenzi, Giulia Annovi, Leon J. Schurgers, Cees Vermeer, Paolo Cianciulli, Ivonne Pasquali Ronchetti, Daniela Quaglino
Izvirni znanstveni članek
Oznake: elastin;oxidative stress;matrix Gla protein;ectopic calcification;beta-thalassemia;
Ectopic calcification in β-thalassemia patients is associated with increased oxidative stress and lower MGP carboxylation
Leto: 2013 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Fibroblast protein profile analysis highlights the role of oxidative stress and vitamin K recycling in the pathogenesis of pseudoxanthoma elasticum
Federica Boraldi, Giulia Annovi, Deanna Guerra, Chiara Paolinelli DeVincenzi, Maria Inmaculada Garcia-Fernandez, Fulvio Panico, Giorgio De Santis, Roberta Tiozzo, Ivonne Pasquali Ronchetti, Daniela Quaglino
Izvirni znanstveni članek
Oznake: ectopic calcification;elastin;fibroblast proteome;MRP6;PXE;
Pseudoxanthoma elasticum (PXE) is a genetic disorder associated to mutations in the ABCC6 gene; however, the pathogenetic mechanisms leading to elastic fibre calcifications and to clinical manifestations are still unknown. Dermal fibroblasts, directly involved in the production of the extracellular ...
Leto: 2009 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Št. zadetkov: 4
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