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Autolysis affects the iron cargo of ferritins in neurons and glial cells at different rates in the human brain
Sowmya Sunkara, Snježana Radulović, Saška Lipovšek Delakorda, Christoph Birkl, Stefan Eggenreich, Anna Maria Birkl-Toeglhofer, Maximilian Schinagl, Daniel Funk, Michael Stöger-Pollach, Johannes Haybaeck, Walter Gössler, Stefan Ropele, Gerd Leitinger
Izvirni znanstveni članek
Oznake: feritin;človeški možgani;transmisijska elektronska mikroskopija z energijskim filtrom;kvantitativno slikanje z magnetno resonanco;avtoliza;ne zaključna dela;ferritin;human brain;energy-filtered transmission electron microscopy;quantitative magnetic resonance imaging;autolysis;
Iron is known to accumulate in neurological disorders, so a careful balance of the iron concentration is essential for healthy brain functioning. An imbalance in iron homeostasis could arise due to the dysfunction of proteins involved in iron homeostasis. Here, we focus on ferritin—the primary iron ...
Leto: 2023 Vir: Fakulteta za naravoslovje in matematiko (UM FNM)
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