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Membrane damage by MBP-1 is mediated by pore formation and amplified by mtDNA
Lea Gigon, Philipp Müller, Beat Haenni, Ioan Iacovache, Maruša Barbo, Gordana Gosheva, Shida Yousefi, Alice Soragni, Christoph von Ballmoos, Benoît Zuber, Hans-Uwe Simon
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Oznake: zunajcelična past;eozinofili;glavna bazična beljakovina;metilacija DNA;tvorba por;mitohondrijske DNA;extracellular trap;eosinophils;major basic protein;DNA methylation;mitochondrial DNA;pore formation;
Eosinophils play a crucial role in host defense while also contributing to immunopathology through the release of inflammatory mediators. Characterized by distinctive cytoplasmic granules, eosinophils securely store and rapidly release various proteins exhibiting high toxicity upon extracellular rel ...
Leto: 2025 Vir: Fakulteta za farmacijo (UL FFA)
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