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Vitamin B3-based biologically active compounds as inhibitors of human cholinesterases
Antonio Zandona, Gabriela Lihtar, Nikola Maraković, Katarina Miš, Valentina Bušić, Dajana Gašo-Sokač, Sergej Pirkmajer, Maja Katalinić
Izvirni znanstveni članek
Oznake: Alzheimerjeva bolezen;nikotinamid;citotoksičnost;Alzheimer's disease;nicotinamide;cytotoxicity;
We evaluated the potential of nine vitamin B3 scaffold-based derivatives as acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitors, as a starting point for the development of novel drugs for treating disorders with cholinergic neurotransmission-linked pathology. As the results indic ...
Leto: 2020 Vir: Medicinska fakulteta (UL MF)
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