Št. zadetkov: 15
Izvirni znanstveni članek
Oznake:
ectopic calcification;fibroblasts;pyrophosphate;pseudoxanthoma elasticum;
Fibroblasts from patients affected by Pseudoxanthoma elasticum exhibit an altered PPi metabolism and are more responsive to pro-calcifying stimuli
Leto:
2014
Vir:
Repozitorij Univerze v Novi Gorici (RUNG)
Izvirni znanstveni članek
Oznake:
autophagic cell death;fat body;IDGF;IPLB-LdFB;proteomics;
Autophagy is an evolutionary ancient process based on the activity of genes conserved from yeast to metazoan taxa. Whereas its role as a mechanism to provide energy during cell starvation is commonly accepted, debate continues about the occurrence of autophagy as a means specifically activated to ac ...
Leto:
2009
Vir:
Repozitorij Univerze v Novi Gorici (RUNG)
Izvirni znanstveni članek
Oznake:
ageing;fibroblast;connective tissue;oxidative stress;protein expression;elastin;
Several studies have analyzed modulation of gene expression during physiological ageing with interesting, but often contradictory results, depending on the model used. In the present report we compare age-related metabolic and synthetic parameters in human dermal fibroblasts (HDF) isolated from youn ...
Leto:
2010
Vir:
Repozitorij Univerze v Novi Gorici (RUNG)
Samostojni znanstveni sestavek ali poglavje v monografski publikaciji
Oznake:
genetic pathology;skin;morphology;PXE;
The Multifaceted Complexity of Genetic Diseases: A Lesson from Pseudoxanthoma Elasticum
Leto:
2011
Vir:
Repozitorij Univerze v Novi Gorici (RUNG)
Izvirni znanstveni članek
Oznake:
collagen type I;alkaline phosphatase;fibroblast;three dimensional gel;morphology;mineralization;
Magnesium Modifies the Structural Features of Enzymatically Mineralized Collagen Gels Affecting the Retraction Capabilities of Human Dermal Fibroblasts Embedded within This 3D System
Leto:
2016
Vir:
Repozitorij Univerze v Novi Gorici (RUNG)
Izvirni znanstveni članek
Oznake:
dermal fibroblasts;primary cell culture;ROS production;serum withdrawal;
The effect of serum deprivation on proliferating cells is well known, in contrast its role on primary
cell cultures, at confluence, has not been deeply investigated. Therefore, in order to explore
the response of quiescent cells to serum deprivation, ubiquitous mesenchymal cells, as normal
human ...
Leto:
2008
Vir:
Repozitorij Univerze v Novi Gorici (RUNG)
Pregledni znanstveni članek
Oznake:
pathology;proteomics;fibrosis;rheumatology;cancer;
Connective tissue consists of cells separated by the extracellular matrix, whose composition and amount vary according
to age, to functional requirements, and to the presence of pathologic conditions. Within this non-random
macromolecular assembly, collagens, elastin, proteoglycans and structural ...
Leto:
2009
Vir:
Repozitorij Univerze v Novi Gorici (RUNG)
Izvirni znanstveni članek
Oznake:
human fibroblast;primary cell cultur;hypoxia;connective tissue;proteome;2D gel electrophoresis;mass-spectrometry;
The ability of cells to respond to changes in oxygen availability is critical for many physiological and pathological processes (i.e. development,
aging, wound healing, hypertension, cancer). Changes in the protein profile of normal human dermal fibroblasts were investigated in vitro after
96 h in ...
Leto:
2007
Vir:
Repozitorij Univerze v Novi Gorici (RUNG)
Izvirni znanstveni članek
Oznake:
genetically modified soybean;liver;mitochondria;
Liver represents a suitable model for monitoring the effects of a diet, due to its key role in controlling the whole metabolism. Although no direct evidence has been reported so far that genetically modified (GM) food may affect health, previous studies on hepatocytes from young female mice fed on G ...
Leto:
2008
Vir:
Repozitorij Univerze v Novi Gorici (RUNG)
Pregledni znanstveni članek
Oznake:
fibroblasts;PXE;PXE-likedisorders;elastin;extracellularmatrix;ectopiccalcification;mesenchymal stromalcells;
Soft connective tissue calcification is not a passive process, but the consequence of metabolic changes of local mesenchymal cells that, depending on both genetic and environmental factors, alter the balance between pro- and anti-calcifying pathways. While the role of smooth muscle cells and pericyt ...
Leto:
2013
Vir:
Repozitorij Univerze v Novi Gorici (RUNG)