Nacionalni portal odprte znanosti

Mehanizmi vezikulacije in stabilnost vezikularnih struktur v vzorcih humane krvne plazme in morskih mikroalg

Darja Božič, Veronika Kralj-Iglič, Ksenija Kogej

Doktorska disertacija

Oznake: biološki vzorci;biološki nanomaterial;brstenje membran;diferencialno centrifugiranje;krvna plazma;morske mikroalge;sedimentacija;zunajcelični vezikli;doktorske disertacije;

Z namenom preučevanja mehanizmov nastanka in stabilnosti submikronskih veziklov v bioloških vzorcih smo analizirali male delce v krvi in kulturah treh vrst morskih mikroalg: Tetraselmis chuii (T. chuii), Dunaliella tertiolecta (D. tertiolecta) in Phaeodactylum tricornutum (P. tricornutum). V krvi in ...

Leto: 2021 Vir: Zdravstvena fakulteta (UL ZF)

Application of dynamic and static light scattering for size and shape characterization of small extracellular nanoparticles in plasma and ascites of ovarian cancer patients

Ksenija Kogej, Ksenija Kogej, Darja Božič, Borut Kobal, Maruša Herzog, Katarina Černe

Izvirni znanstveni članek

Oznake: ekstracelularni vezikli;zunajcelični nanodelci;rak jajčnikov;extracellular vesicles;extracellular nanoparticles;ovarian cancer;

In parallel to medical treatment of ovarian cancer, methods for the early detection of cancer tumors are being sought. In this contribution, the use of non-invasive static (SLS) and dynamic light scattering (DLS) for the characterization of extracellular nanoparticles (ENPs) in body fluids of advanc ...

Leto: 2021 Vir: Medicinska fakulteta (UL MF)

Applicability of platelet- and extracellular vesicle-rich plasma in medicine

Domen Vozel, Marko Jeran, Darja Božič, Ljubiša Pađen, Manca Pajnič, Bojana Uršič, Veronika Kralj-Iglič, Saba Battelino

Objavljeni znanstveni prispevek na konferenci (vabljeno predavanje)

Oznake: platelets;platelet-rich plasma;extracellular vesicles;regenerative effects;haemostasis;immune response;blood immune cells;

Platelet-rich plasma is a blood-derived product with proven favourable effects after a local application in various healing disorders. It is also rich with extracellular vesicles - a heterogeneous group of nano- to micro-sized membranous structures -that are considered as the main mediators of regen ...

Leto: 2019 Vir: Zdravstvena fakulteta (UL ZF)

Viscosity of plasma as a key factor in assessment of extracellular vesicles by light scattering

Darja Božič, Simona Prelesnik, Ita Junkar, Roman Štukelj, Manca Pajnič, Ema Žagar, Veronika Kralj-Iglič, Ksenija Kogej

Izvirni znanstveni članek

Oznake: izvencelični vezikli;eksosomi;krvna plazma;dinamično sipanje svetlobe;statično sipanje svetlobe;določanje oblike;viskoznost krvne plazme;extracellular vesicles;exosomes;blood plasma;dynamic light scattering;static light scattering;shape characterization;viscosity of blood plasma;

Extracellular vesicles (EVs) isolated from biological samples are a promising material for use in medicine and technology. However, the assessment methods that would yield repeatable concentrations, sizes and compositions of the harvested material are missing. A plausible model for the description o ...

Leto: 2019 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)

Scanning electron microscope images of Dunaliella tertiolecta culture

Apolonija Bedina Zavec, Darja Božič, Matej Hočevar, Aleš Iglič, Marko Jeran, Veronika Kralj-Iglič, Anna Romolo