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Št. zadetkov: 4
Connective tissue and diseases
Daniela Quaglino, Federica Boraldi, Giulia Annovi, Deanna Guerra, Ivonne Pasquali Ronchetti
Pregledni znanstveni članek
Oznake: pathology;proteomics;fibrosis;rheumatology;cancer;
Connective tissue consists of cells separated by the extracellular matrix, whose composition and amount vary according to age, to functional requirements, and to the presence of pathologic conditions. Within this non-random macromolecular assembly, collagens, elastin, proteoglycans and structural ...
Leto: 2009 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Heparan sulfate affects elastin deposition in fibroblasts cultured from donors of different ages
Giulia Annovi, Federica Boraldi, Pasquale Moscarelli, Deanna Guerra, Roberta Tiozzo, Bruna Parma, Pascal Sommer, Daniela Quaglino
Izvirni znanstveni članek
Oznake: heparan sulfate;elastin;fibroblasts;
Heparan sulfate (HS), due to its presence on the cell surface and in the extracellular milieu and its ability to modulate cell signaling, has a fundamental role in both physiological and pathological conditions. For decades we have demonstrated the occurrence of interactions between glycosaminogly ...
Leto: 2012 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Matrix gla protein and alkaline phosphatase are differently modulated in human dermal fibroblasts from PXE patients and controls
Federica Boraldi, Giulia Annovi, Cees Vermeer, Leon J. Schurgers, Tommaso Trenti, Roberta Tiozzo, Deanna Guerra, Daniela Quaglino
Izvirni znanstveni članek
Oznake: fibroblast;vitamin K;elastin calcification;proteomics;
Matrix Gla Protein and Alkaline Phosphatase Are Differently Modulated in Human Dermal Fibroblasts from PXE Patients and Controls
Leto: 2013 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Fibroblast protein profile analysis highlights the role of oxidative stress and vitamin K recycling in the pathogenesis of pseudoxanthoma elasticum
Federica Boraldi, Giulia Annovi, Deanna Guerra, Chiara Paolinelli DeVincenzi, Maria Inmaculada Garcia-Fernandez, Fulvio Panico, Giorgio De Santis, Roberta Tiozzo, Ivonne Pasquali Ronchetti, Daniela Quaglino
Izvirni znanstveni članek
Oznake: ectopic calcification;elastin;fibroblast proteome;MRP6;PXE;
Pseudoxanthoma elasticum (PXE) is a genetic disorder associated to mutations in the ABCC6 gene; however, the pathogenetic mechanisms leading to elastic fibre calcifications and to clinical manifestations are still unknown. Dermal fibroblasts, directly involved in the production of the extracellular ...
Leto: 2009 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Št. zadetkov: 4
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