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Št. zadetkov: 2
Fiziološka vloga MAGEL2 pri sindromih Prader-Willi in Schaaf-Yang
Denis Štepihar, Klementina Fon Tacer, Uroš Petrovič, Marko Kreft
Magistrsko delo
Oznake: Prader-Willi;Schaaf-Yang;MAGE;MAGEL2;prenos western;imunoprecipitacija;
MAGEL2 je eden izmed največjih proteinov v družini melanomskih antigenov (MAGE), katerega gen se nahaja na kromosomu 15 (15q11-q13), regiji, odgovorni za nastanek sindroma Prader-Willi (PWS). Geni, zapisani na tem delu kromosoma 15, so vtisnjeni na materinem alelu in izraženi po očetovi strani; izgu ...
Leto: 2025 Vir: Biotehniška fakulteta (UL BF)
Cross-species upregulation of MAGED2 in liver cancer suggests a role in obesity-driven tumor progression
Tara Bayat, Farzana Yeasmin Popy, Rebecca R. Florke Gee, Benjamin Barr, Yusuff Olayiwola, Juan Sebastian Solano Gutierrez, Denis Štepihar, Jorge Diaz-Riaño, Stephanie Myers, Kaja Blagotinšek Cokan, Damjana Rozman
Izvirni znanstveni članek
Oznake: cancer-testis antigen (CTA);comparative cancer research;hepatocellular carcinoma;high-fat diet;liver tumors;melanoma-associated antigen (MAGE);obesity;
Melanoma-associated antigens (MAGEs) are cancer-testis antigens (CTAs) aberrantly expressed in multiple cancer types, including hepatocellular carcinoma (HCC), and associated with aggressive phenotypes. Although MAGE proteins are widely studied as cancer immunotherapy targets, their roles in HCC and ...
Leto: 2026 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 2
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