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Development of an animal model to study the role of the phosphatase PTPN22 in the pathogenesis of chronic lymphocytic leukemia
Öznur Özlem İbrahimoğlu, Dimitar Efremov
Doktorska disertacija
Oznake: PTPN22;BCR signalling;B1 B cells;marginal zone B cells;chronic lymphocytic leukemia (CLL);autoimmunity.;
A polymorphic variant of the phosphatase PTPN22 has recently emerged as a major risk factor for the development of multiple autoimmune diseases. The mechanism how this variant increases the susceptibility for autoimmune diseases is still unclear. A recent study by our lab showed that PTPN22 is marke ...
Leto: 2017 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
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