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Št. zadetkov: 2
Reduced ATP turnover during hibernation in relaxed skeletal muscle
Cosimo De Napoli, Luisa Schmidt, Mauro Montesel, Laura Cussonneau, Samuele Sanniti, Lorenzo Marcucci, Elena Germinario, Jonas Kindberg, Alina L. Evans, Marco Narici
Izvirni znanstveni članek
Oznake: translacijsko raziskovanje;živalska fiziologija;presnova;translational research;animal physiology;metabolism;
Hibernating brown bears, due to a drastic reduction in metabolic rate, show only moderate muscle wasting. Here, we evaluate if ATPase activity of resting skeletal muscle myosin can contribute to this energy sparing. By analyzing single muscle fibers taken from the samebears,eitherduring hibernationo ...
Leto: 2025 Vir: Repozitorij Univerze na Primorskem (RUP)
Mitochondria can substitute for parvalbumin to lowercytosolic calcium levels in the murine fast skeletal muscle
Lorenzo Marcucci, Leonardo Nogara, Marta Canato, Elena Germinario, Anna Raffaello, Michela Carraro, Paolo Bernardi, Laura Pietrangelo, Simona Boncompagni, Feliciano Protasi, Nazareno Paolocci, Carlo Reggiani
Izvirni znanstveni članek
Oznake: calcium;mitochondria;mouse skeletal muscle fibers;parvalbumin;reaction-diffusion model;
Aim: Parvalbumin (PV) is a primary calcium buffer in mouse fast skeletal musclefibers. Previous work showed that PV ablation has a limited impact on cytosolicCa2+ ([Ca2+]cyto) transients and contractile response, while it enhances mitochon-drial density and mitochondrial matrix-free calcium concentr ...
Leto: 2024 Vir: Univerza na Primorskem (UP)
Št. zadetkov: 2
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