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Expression of FGFR1-4 in malignant pleural mesothelioma tissue and corresponding cell lines and its relationship to patient survival and FGFR inhibitor sensitivity
Gregor Vlačić, Mir Alireza Hoda, Thomas Klikovits, Katharina Sinn, Elisabeth Gschwandtner, Katja Mohorčič, Karin Schelch, Christine Pirker, Barbara Peter-Vörösmarty, Jelena Brankovic, Tanja Čufer, Aleš Rozman, Izidor Kern
Izvirni znanstveni članek
Oznake: maligni plevralni mezoteliom;receptorji za fibroblastne rastne dejavnike;azbest;imunoterapija;kemoterapija;genomska analiza;infigratinib;malignant pleural mesothelioma;fibroblast growth factor receptors;azbestos;immunotherapy;chemotherapy;genomic analysis;
Malignant pleural mesothelioma (MPM) is a devastating malignancy with limited therapeutic options. Fibroblast growth factor receptors (FGFR) and their ligands were shown to contribute to MPM aggressiveness and it was suggested that subgroups of MPM patients could benefit from FGFR-targeted inhibitor ...
Leto: 2019 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
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