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Št. zadetkov: 7
Single cell transcriptome data analysis of human and mice beta cells from diabetic and non-diabetic donors
Eva Lavrenčič, Jernej Jakše, Fabian J. Theis, Jernej Kovač
Magistrsko delo
Oznake: beta-cell heterogeneity;diabetes;humans;mice;pancreatic islets;scRNA-seq data analysis;species comparison;
Pancreatic β-cells, which are a highly plastic, heterogeneous group of cells, produce insulin and have a key role in glucose homeostasis. Because malfunctioning of β-cells causes diabetes, they represent a potential target for diabetes regenerative therapies. Since most diabetes studies are done on ...
Leto: 2024 Vir: Biotehniška fakulteta (UL BF)
Effect of sample handling on gene expression in single cells of islets of Langerhans
Katarina Valentinčič, Jernej Jakše, Fabian J. Theis, Matevž Likar
Magistrsko delo
Oznake: batch effects;beta cells;bioinformatics;type 2 diabetes;differential gene expression analysis;scRNA-seq;gene set enrichment analysis;
This study investigates how sample preparation, storage, and processing impact gene expression analysis in single cells of pancreatic islets, with an emphasis on distinguishing technical artefacts from actual biological changes, especially in the context of Type 2 Diabetes (T2D). We found that batch ...
Leto: 2024 Vir: Biotehniška fakulteta (UL BF)
fMRI-based decoding of the modified default-mode network in mild cognitive impairment
Fabian Theis
Video in druga učna gradiva
Oznake: computer science;image analysis;fmri - analysis
The diagnostic tool to detect early stages of Alzheimer’s Disease, a progressive neurodegenerative disease, is lacking until today. FDG-PET (Fluorodeoxyglucose-Positron Emission Tomography) shows hypometabolic areas in the brains of pre-demented, i.e. patients suffering from mild cognitive impair ...
Leto: 2006 Vir: videolectures.net
A trust-region method for stochastic variational inference with applications to streaming data
Lucas Theis
Video in druga učna gradiva
Oznake: computer science;machine learning
Stochastic variational inference allows for fast posterior inference in complex Bayesian models. However, the algorithm is prone to local optima which can make the quality of the posterior approximation sensitive to the choice of hyperparameters and initialization. We address this problem by replaci ...
Leto: 2015 Vir: videolectures.net
A note on the evaluation of generative models
Lucas Theis
Video in druga učna gradiva
Oznake: computer science;machine learning
Probabilistic generative models can be used for compression, denoising, inpainting, texture synthesis, semi-supervised learning, unsupervised feature learning, and other tasks. Given this wide range of applications, it is not surprising that a lot of heterogeneity exists in the way these models are ...
Leto: 2016 Vir: videolectures.net
Management of urban waters with nature-based solutions in circular cities
Oral Hasan Volkan, Matej Radinja, Anacleto Rizzo, Katharina Kearney, Theis Raaschou Andersen, Pawel Krzeminski, Gianluigi Buttiglieri, Derya Ayral-Cinar, Joaquim Comas, Magdalena Gajewska, Marco Hartl, David Christian Finger, Jan K. Kazak, Harri Mattila, Patricia I. Vieira, Patrizia Piro, Stefania Anna Palermo, Michele Turco, Behrouz Pirouz, Alexandros Stefanakis, Martin Regelsberger, Nadia Ursino, Pedro Carvalho
Izvirni znanstveni članek
Oznake: modro-zelena infrastruktura;blaženje podnebnih sprememb;trajnostno upravljanje voda;izzivi urbanega kroženja snovi;ponovna uporaba vode;blue-green infrastructure;climate change and mitigation;sustainable water management;urban circularity challenges;water reuse;
Nature-Based Solutions (NBS) have been proven to effectively mitigate and solve resource depletion and climate-related challenges in urban areas. The COST (Cooperation in Science and Technology) Action CA17133 entitled “Implementing nature-based solutions (NBS) for building a resourceful circular ci ...
Leto: 2021 Vir: Fakulteta za gradbeništvo in geodezijo (UL FGG)
Towards a cross-sectoral view of nature-based solutions for enabling circular cities
Günter Langergraber, Joana A. C. Castellar, Theis Raaschou Andersen, Maria-Beatrice Andreucci, Gösta F. M. Baganz, Gianluigi Buttiglieri, Alba Canet-Martí, Pedro Carvalho, David Christian Finger, Tjaša Griessler Bulc, Ranka Junge-Berberovic, Boldizsár Megyesi, Dragan Milošević, Oral Hasan Volkan, David Pearlmutter, Rocío Pineda-Martos, Bernhard Pucher, Eric D. Van Hullebusch, Nataša Atanasova
Izvirni znanstveni članek
Oznake: izzivi krožnosti;večnamenskost;interdisciplinarnost;naravne rešitve;mestni sektorji;trajnostni razvoj mest;ekosistemsko upravljanje;circularity challenges;multifunctionality;interdisciplinary;nature-based solutions;urban sectors;sustainable urban development;ecosystem-based management;
A framework developed by the COST Action Circular City (an EU-funded network of 500+ scientists from 40+ countries; COST = Cooperation in Science and Technology) for addressing Urban Circularity Challenges (UCCs) with nature-based solutions (NBSs) was analyzed by various urban sectors which refer to ...
Leto: 2021 Vir: Zdravstvena fakulteta (UL ZF)
Št. zadetkov: 7
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