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Št. zadetkov: 3
fMRI-based decoding of the modified default-mode network in mild cognitive impairment
Fabian Theis
Video in druga učna gradiva
Oznake: computer science;image analysis;fmri - analysis
The diagnostic tool to detect early stages of Alzheimer’s Disease, a progressive neurodegenerative disease, is lacking until today. FDG-PET (Fluorodeoxyglucose-Positron Emission Tomography) shows hypometabolic areas in the brains of pre-demented, i.e. patients suffering from mild cognitive impair ...
Leto: 2006 Vir: videolectures.net
Single cell transcriptome data analysis of human and mice beta cells from diabetic and non-diabetic donors
Eva Lavrenčič, Jernej Jakše, Fabian J. Theis, Jernej Kovač
Magistrsko delo
Oznake: beta-cell heterogeneity;diabetes;humans;mice;pancreatic islets;scRNA-seq data analysis;species comparison;
Pancreatic β-cells, which are a highly plastic, heterogeneous group of cells, produce insulin and have a key role in glucose homeostasis. Because malfunctioning of β-cells causes diabetes, they represent a potential target for diabetes regenerative therapies. Since most diabetes studies are done on ...
Leto: 2024 Vir: Biotehniška fakulteta (UL BF)
Effect of sample handling on gene expression in single cells of islets of Langerhans
Katarina Valentinčič, Jernej Jakše, Fabian J. Theis, Matevž Likar
Magistrsko delo
Oznake: batch effects;beta cells;bioinformatics;type 2 diabetes;differential gene expression analysis;scRNA-seq;gene set enrichment analysis;
This study investigates how sample preparation, storage, and processing impact gene expression analysis in single cells of pancreatic islets, with an emphasis on distinguishing technical artefacts from actual biological changes, especially in the context of Type 2 Diabetes (T2D). We found that batch ...
Leto: 2024 Vir: Biotehniška fakulteta (UL BF)
Št. zadetkov: 3
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