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Št. zadetkov: 3
Bacterial cytoplasm as an effective cell compartment for producing functional VHH-based affinity reagents and Camelidae IgG-like recombinant antibodies
Selma Djender, Aurelie Schneider, Anne Beugnet, Ronan Crepin, Klervi Even Desrumeaux, Chiara Romani, Sandrine Moutel, Franck Perez, Ario De Marco
Izvirni znanstveni članek
Oznake: recombinant antibodies;cytoplasmic expression;functional tags;
Bacterial cytoplasm as an effective cell compartment for producing functional VHH-based affinity reagents and Camelidae IgG-like recombinant antibodies
Leto: 2014 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
NaLi-H1
Sandrine Moutel, Nicolas Bery, Virginie Bernard, Laura Keller, Emilie Lemesre, Ario De Marco, Laetitia Ligat, Jean-Christophe Rain, Gilles Favre, Aurelien Olichon, Franck Perez
Izvirni znanstveni članek
Oznake: nanobodies;synthetic phage display library;in vitro panning;
In vitro selection of antibodies allows to obtain highly functional binders, rapidly and at lower cost. Here, we describe the first fully synthetic phage display library of humanized llama single domain antibody (NaLi-H1: Nanobody Library Humanized 1). Based on a humanized synthetic single domain ...
Leto: 2016 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Nanobodies against surface biomarkers enable the analysis of tumor genetic heterogeneity in uveal melanoma patient-derived xenografts
Ronan Crepin, David Gentien, Angeline Duché, Audrey Rapinat, Cecile Reyes, Fariba Némati, Gérald Massonnet, Didier Decaudin, Selma Djender, Sandrine Moutel, Klervi Even Desrumeaux, Nathalie Cassoux, Sophie Piperno-Neumann, Sebastian Amigorena, Franck Perez, Sergio Roman-Roman, Ario De Marco
Izvirni znanstveni članek
Oznake: nanobodies;uveal melanoma;patient derived xenografts;MUC18;membrane surface biomarkers;panning;tumor polyclonality;
Monoclonal antibodies specific for biomarkers expressed on the surface of uveal melanoma (UM) cells would simplify the immune-capture and genomic characterization of heterogeneous tumor cells originated from patient derived xenografts (PDXs). Antibodies against four independent tumor antigens were i ...
Leto: 2017 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Št. zadetkov: 3
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