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Št. zadetkov: 5
ǂAn ǂefficient protein evolution workflow for the improvement of bacterial PET hydrolyzing enzymes
Valentina Pirillo, Marco Orlando, Davide Tessaro, Loredano Pollegioni, Gianluca Molla
Izvirni znanstveni članek
Oznake: biocatalysis;biodegradation;protein engineering;polyethylene terephthalate;hydrolases;
Enzymatic degradation is a promising green approach to bioremediation and recycling of the polymer poly(ethylene terephthalate) (PET). In the past few years, several PET-hydrolysing enzymes (PHEs) have been discovered, and new variants have been evolved by protein engineering. Here, we report on a s ...
Leto: 2022 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Efficient polyethylene terephthalate degradation at moderate temperature
Valentina Pirillo, Marco Orlando, Caren Battaglia, Loredano Pollegioni, Gianluca Molla
Izvirni znanstveni članek
Oznake: green technology;improved LCC;polyethylene terephthalate;biodegradation;rational design;
Enzymatic degradation of poly(ethylene terephthalate) (PET) is becoming a reality because of the identification of novel PET‐hydrolysing enzymes (PHEs) and the engineering of evolved enzyme variants. Here, improved variants of leaf‐branch compost cutinase (LCC), a thermostable enzyme isolated by a m ...
Leto: 2023 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Microbial enzyme biotechnology to reach plastic waste circularity
Marco Orlando, Gianluca Molla, Pietro Castellani, Valentina Pirillo, Vincenzo Torretta, Navarro Ferronato
Pregledni znanstveni članek
Oznake: circular bioeconomy;biotechnology;solid waste management;biodegradation;synthetic plastic;
The accumulation of synthetic plastic waste in the environment has become a global concern. Microbial enzymes (purified or as whole-cell biocatalysts) represent emerging biotechnological tools for waste circularity; they can depolymerize materials into reusable building blocks, but their contributio ...
Leto: 2023 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Electroconductive bionanocomposites from black soldier fly proteins for green flexible electronics
Edoardo Testa, Vincenzina Barbera, Elisa Fasoli, Ulrich Giese, Maria Rosaria Belviso, Pasqua Rossini, Daniele Bruno, Gianluca Tettamanti, Marco Orlando, Gianluca Molla
Izvirni znanstveni članek
Oznake: proteins;nanocomposite;black soldier fly;organic waste;flexible electronics;
Printed and flexible electronics hold the potential to revolutionize the world of electronic devices. A primary focus today is their circularity, which can be achieved by using biobased materials. In this study, electrically conductive bionanocomposite materials suitable for flexible electronics wer ...
Leto: 2025 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
ǂA ǂcrucial active site network of titratable residues guides catalysis and NAD[sup]+ binding in human succinic semialdehyde dehydrogenase
Samuele Cesaro, Marco Orlando, Ilaria Bettin, Carmen Longo, Giulia Spagnoli, Patrizia Polverino de Laureto, Gianluca Molla, Mariarita Bertoldi
Izvirni znanstveni članek
Oznake: bioinformatic analysis;evolutionary analysis;enzymatic mechanism;kinetics;succinic semialdehyde dehydrogenase;succinic semialdehyde dehydrogenase deficiency;
Human succinic semialdehyde dehydrogenase is a mitochondrial enzyme fundamental in the neurotransmitter γ‐aminobutyric acid catabolism. It catalyzes the NAD+‐dependent oxidative degradation of its derivative, succinic semialdehyde, to succinic acid. Mutations in its gene lead to an inherited neurome ...
Leto: 2025 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Št. zadetkov: 5
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