Iskalni niz:
išči po
išči po
išči po
išči po
Vrsta gradiva:
Jezik:
Št. zadetkov: 1
IDH1-mutant cancer cells are sensitive to cisplatin and an IDH1-mutant inhibitor counteracts this sensitivity
Mohammed Khurshed, Niels Aarnoudse, Renske Hulsbos, Vashendriya V. V. Hira, Hanneke WM van Laarhoven, Johanna W Wilmink, Remco J. Molenaar, Cornelis J. F. van Noorden
Izvirni znanstveni članek
Oznake: izocitrat dehidrogenaza;kemosenzibilnost;cis-diamminedichloroplatinum;2-hidroksiglutarat;isocitrate dehydrogenase;chemosensitivity;2-hydroxyglutarate;
Isocitrate dehydrogenase (IDH1)-1 is mutated in various types of human cancer, and the presence of this mutation is associated with improved responses to irradiation and chemotherapy in solid tumor cells. Mutated IDH1 (IDH1MUT) enzymes consume NADPH to produce D-2-hydroxyglutarate (D-2HG) resulting ...
Leto: 2018 Vir: Nacionalni inštitut za biologijo (NIB)
Št. zadetkov: 1
Ključne besede:
Leto izdaje:
Avtorji:
Repozitorij:
Tipologija:
Jezik: