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Št. zadetkov: 2
Physiologically achievable concentration of 2-deoxy-D-glucose stimulates IFN-γ secretion in activated T cells in vitro
Jernej Repas, Tjaša Frlic, Tadeja Snedec, Andreja Nataša Kopitar, Harald Sourij, Andrej Janež, Mojca Pavlin, Mojca Pavlin
Izvirni znanstveni članek
Oznake: T cells;interferon gamma;2-deoxy-D-glucose;
2-deoxy-D-glucose (2DG) is a glycolysis and protein N-glycosylation inhibitor with promising anti-tumor and immunomodulatory effects. However, 2DG can also suppress T cell function, including IFN-γ secretion. Few human T cell studies have studied low-dose 2DG, which can increase IFN-γ in a Jurkat cl ...
Leto: 2024 Vir: Repozitorij Univerze v Ljubljani (RUL)
Retinal venular vessel diameters are smaller during ten days of bed rest
Adam Salon, Göktuğ Mert Çiftci, Damir Zubac, Boštjan Šimunič, Rado Pišot, Marco Narici, Per Morten Fredriksen, Benedicta Ngwenchi Nkeh-Chungag, Harald Sourij, Nandu Goswami
Izvirni znanstveni članek
Oznake: oko;mrežnica;venske žile;ležanje v postelji;gibalna neaktivnost;eyes;retinal venular vessel;bed rest;
Older individuals experience cardiovascular dysfunction during extended bedridden hospital or care home stays. Bed rest is also used as a model to simulate accelerated vascular deconditioning occurring during spacefight. This study investigates changes in retinal microcirculation during a tenday bed ...
Leto: 2023 Vir: Univerza na Primorskem (UP)
Št. zadetkov: 2
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