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Št. zadetkov: 83
Research progress and applications of multivalent, multispecific and modified nanobodies for disease treatment
Jiewen Wang, Guangbo Kang, Haibin Yuan, Xiaocang Cao, He Huang, Ario De Marco
Pregledni znanstveni članek
Oznake: nanobody multimers;immunomodulation;intrabodies;imaging;nanobody functionalization;
Research progress and applications of multivalent, multispecific and modified nanobodies for disease treatment
Leto: 2022 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Effect of humanizing mutations on the stability of the llama single-domain variable region
Miguel A. Soler, Barbara Medagli, Jiewen Wang, Sandra Oloketuyi, Gregor Bajc, He Huang, Sara Fortuna, Ario De Marco
Izvirni znanstveni članek
Oznake: nanobody framework;modeling;nanobody humanization;CDR grafting;
Effect of humanizing mutations on the stability of the llama single-domain variable region
Leto: 2021 Vir: Biotehniška fakulteta (UL BF)
Design of nanobody-based bispecific constructs by in silico affinity maturation and umbrella sampling simulations
Zixuan Bai, Jiewen Wang, Jiaqi Liu, Haibin Yuan, Ping Wang, Miao Zhang, Yuanhang Feng, Xiangtong Cao, Xiangan Cao, Guangbo Kang, Ario De Marco, He Huang
Izvirni znanstveni članek
Oznake: nanobody rational design;bispecific binders;protein activity inhibition;
Design of nanobody-based bispecific constructs by in silico affinity maturation and umbrella sampling simulations
Leto: 2023 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Affinity maturation of antibody fragments
Jiaqi Liu, Guangbo Kang, Jiewen Wang, Haibin Yuan, Yili Wu, Shuxian Meng, Ping Wang, Miao Zhang, Yuli Wang, Yuanhang Feng, He Huang, Ario De Marco
Pregledni znanstveni članek
Oznake: deep learning;protein modeling;random mutagenesis;rational mutagenesis;
Affinity maturation of antibody fragments
Leto: 2023 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
A Novel Transition Based Encoding Scheme for Planning as Satisfiability
Ruoyun Huang
Video in druga učna gradiva
Oznake: computer science;artificial intelligence
Planning as satisfiability is a principal approach to planning with many eminent advantages. The existing planning as satisfiability techniques usually use encodings compiled from the STRIPS formalism. We introduce a novel SAT encoding scheme based on the SAS+ formalism. It exploits the structural i ...
Leto: 2010 Vir: videolectures.net
Adaptive Fourier-Domain Inference on the Symmetric Group
Jonathan Huang
Video in druga učna gradiva
Oznake: computer science;machine learning;markov processes
Leto: 2008 Vir: videolectures.net
Probability Distributions on Permutations: Compact Representations and Inference
Jonathan Huang
Video in druga učna gradiva
Oznake: computer science;machine learning
Permutations arise in a variety of real-world problems, such as voting, ranking, and data association. Representing uncertainty over permutations, however, is difficult since there are n! permutations, and unlike many problems, they cannot be represented effectively by graphical models due to the mu ...
Leto: 2008 Vir: videolectures.net
Poster: Using Participant Role in Multiparty Meetings as Prior Knowledge for Nonparametric Topic Modeling
Songfang Huang
Video in druga učna gradiva
Oznake: computer science;machine learning
In this paper we introduce our attempts to incorporate the participant role information in multiparty meetings for document modeling using the hierarchical Dirichlet process. The perplexity and automatic speech recognition results demonstrate that the participant role information is a promising pri ...
Leto: 2008 Vir: videolectures.net
Learning with Structured Sparsity
Junzhou Huang
Video in druga učna gradiva
Oznake: computer science;machine learning;statistical learning
This paper investigates a new learning formulation called structured sparsity, which is a natural extension of the standard sparsity concept in statistical learning and compressive sensing. By allowing arbitrary structures on the feature set,this concept generalizes the group sparsity idea. A gene ...
Leto: 2009 Vir: videolectures.net
Using Semantic Distances for Reasoning with Inconsistent Ontologies
Zhisheng Huang
Video in druga učna gradiva
Oznake:
Re-using and combining multiple ontologies on the Web is bound to lead to inconsistencies between the combined vocabularies. Even many of the ontologies that are in use today turn out to be inconsistent once some of their implicit knowledge is made explicit. However, robust and efficient methods to ...
Leto: 2008 Vir: videolectures.net
Št. zadetkov: 83
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