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Biological evaluation of Valeriana extracts from Argentina with potent cholinesterase inhibition for the treatment of neurodegenerative disorders and their comorbidities—The case of Valeriana carnosa Sm. (Caprifoliaceae) studied in mice
Carolina Marcucci, Marina Rademacher, Fabiola Kamecki, Valentina Pastore, Hernán Gerónimo Bach, Rafael Alejandro Ricco, Marcelo Luis Wagner, Damijan Knez, Stanislav Gobec, Natalia Colettis, Mariel Marder
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Oznake: acetilholinesteraza;agregacija β-amiloida;monoaminooksidaza;spomin;Alzheimer’s disease;medicinal plant;acetylcholinesterase;antioxidant;β-amyloid aggregation;monoamine oxidase;memory;antidepressant;
Alzheimer’s disease (AD) is a neurodegenerative disorder whose pathophysiology includes the abnormal accumulation of proteins (e.g., β-amyloid), oxidative stress, and alterations in neurotransmitter levels, mainly acetylcholine. Here we present a comparative study of the effect of extracts obtained ...
Leto: 2023 Vir: Fakulteta za farmacijo (UL FFA)
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