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Št. zadetkov: 2
Expansive growth of two glioblastoma stem-like cell lines is mediated by bFGF and not by EGF
Neža Podergajs, Narve Brekka, Bernhard Radlwimmer, Christel Herold-Mende, Krishna M. Talasila, Katja Tiemann, Uroš Rajčević, Tamara Lah Turnšek, Rolf Bjerkvig, Hrvoje Miletic
Objavljeni znanstveni prispevek na konferenci
Oznake: glioblastoma;stem cell cultures;bFGF;
Background. Patient-derived glioblastoma (GBM) stem-like cells (GSCs) represent a valuable model for basic and therapeutic research. GSCs are usually propagated in serum-free Neural Basal medium supplemented with bFGF and EGF. Yet, the exact influence of these growth factors on GSCs is still unclear ...
Leto: 2013 Vir: Onkološki inštitut Ljubljana (OI)
Transmembrane protein CD9 is glioblastoma biomarker, relevant for maintenance of glioblastoma stem cells
Neža Podergajs, Helena Motaln, Uroš Rajčević, Urška Verbovšek, Marjan Koršič, Nina Obad, Heidi Espedal, Miloš Vittori, Christel Herold-Mende, Hrvoje Miletic, Rolf Bjerkvig, Tamara Lah Turnšek
Izvirni znanstveni članek
Oznake: biomarker;CD9;glioblastoma stem cells;neural stem cells;tetraspanin;
The cancer stem cell model suggests that glioblastomas contain a subpopulation of stem-like tumor cells that reproduce themselves to sustain tumor growth. Targeting these cells thus represents a novel treatment strategy and therefore more specific markers that characterize glioblastoma stem cells ne ...
Leto: 2016 Vir: Nacionalni inštitut za biologijo (NIB)
Št. zadetkov: 2
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